Cellular Immunology & Assay Development - Senior Scientist
- Experience Level
- Experienced (non-manager)
To lead validation of novel biological targets, performing and analyzing experiments in the field of immune-oncology and autoimmune diseases to deliver the next wave of novel therapeutic concepts. We are looking for an experienced, independent and flexible team player.
Lead the identification and validation of new therapeutic concepts to build the portfolio in immuno-oncology and autoimmune diseases.
Lead, develop, perform and analyze immunological assays including but not limited to immuno-oncology assays such as immune profiling using multi-color flow cytometry, multiplex cytokine profiling, gene expression profiling, ELISA, binding assays and functional primary human cell-based assays for the characterization of novel biological candidates.
Perform cell culture, including primary human cultures, development and maintenance of cell lines.
Contribute to inter-disciplinary research efforts in a cross-functional setting.
Design, perform and analyze experiments and communicate results in a timely manner.
Maintain experimental records in electronic laboratory notebook format.
Review relevant scientific literature, experimental design, troubleshooting, analysis and interpretation of data
Assist with general laboratory duties including lab equipment maintenance, ordering and receiving of lab supplies.
Lead external collaborations to build the portfolio as needed
Comply with all safety guidelines
Perform other relevant responsibilities as required.
Manage a small team of direct reports
PhD (entry level) or Master’s degree in immunology, cellular biology or related life sciences with at least 5 years of experience in drug discovery
Solid and demonstrable bench level experience in the development, validation and implementation of immunological assays
Hands-on expertise in methodologies, reagents and instruments used for primary cell cultures, flow cytometry (mandatory), ELISA and cytokine analyses
Experience with handling primary cells in BSL-2 level facilities, isolation of immune cells from human biological samples (PBMC) is mandatory. Practical knowledge in data analysis using standard software (e.g. Excel, GraphPad, JMP, Flow cytometry dedicated software)
Experience in antibody discovery and pharmaceutical industry is a plus
Excellent written and verbal communication skills in English; proficiency in French is a plus
Strong organizational skills with the capacity to handle multiple tasks simultaneously
Ability to work independently as well as part of a cross-functional team
Strong interpersonal communication skills
Excellent lab management skills and mentoring skills
Strong work ethic and willingness to participate in a fast-paced work environment
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