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Senior Scientist, Proteomics

Employer
Oxford BioMedica (UK) Limited
Location
Oxford
Salary
Competitive
Start date
17 Sep 2019
Closing date
15 Oct 2019

View more

Discipline
R & D
Hours
Full Time
Contract Type
Permanent
Experience Level
Experienced (non-manager)

Job Details

Oxford BioMedica is a pioneer of gene and cell therapy and our work is helping to deliver life changing treatments.

Gene and cell therapy is the treatment of disease by the delivery of therapeutic DNA into a patient’s cells, providing long term and potentially curative treatments for a wide range of diseases. With the potential to transform medicine, the sector holds significant promise with the first commercial products now launched and others rapidly approaching the market.

Our recent successes are driving significant growth.  As such, we are looking for a Senior Scientist, Proteomics.  The purpose of this role is the development of Mass Spectrometry based protein analytics.

The role responsibilities and deliverables are:

  • Perform sample preparation for use in mass spectrometric techniques for the analysis of proteins
  • Generate MS data to characterise cells and complex protein mixtures
  • Analyse MS data using Protein Discovery, Maxquant and Spectronaut
  • Provide basic statistic and bioinformatics analysis of MS data, interpret and present data at internal meetings and external conferences
  • Develop Parallel reaction monitoring (PRM) for the quantitation of peptides
  • Perform tissue culture and labelling experiments
  • Provide technical support accross functions at OXB
  • Contribute to research-related activities within Oxford Biomedica
  • Collaborate with other research departments
  • Assay and MS instrument troubleshooting
  • Carry on research-related administration (Maintain consumable stocks, generate SOP&ROP, Risk assessment)
  • Independently manage daily research activities and support junior members of staff

To be successful in the role, you will have:

  • A Master degree in the area of biology, biochemistry, cell biology or similar; Ideally a PhD in relevant field of studies
  • A solid background in mass spectrometry-based proteomics, ideally with experience in analysing complex protein mixtures and cells
  • A background in biological sciences with a strong interest in learning and applying mass spectrometry in research
  • High level analytical capability
  • Proven track record of mass spectrometric usage, trouble shooting and application in research
  • Implementation of new innovative techniques and technologies
  • Excellent knowledge of protein chemistry, cell biology or virology

Your personal attributes will include:

  • Proven record of independent working and collaborative working
  • Happy working within a team and able to contribute in their area of expertise
  • Ability to communicate complex information clearly
  • Excellent oral and written communication skills
  • Excellent Interpersonal skills
  • Proven track record of Influencing decision making processes
  • Self-motivated and provocative working approach
  • Enthusiastic and innovative scientist
  • Able to meet deadlines

No agencies please

Company

Oxford Biomedica is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, Oxford Biomedica has more than 25 years of experience in viral vectors, the driving force behind the majority of gene therapies.  

Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patient’s cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients’ cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).  

Oxford Biomedica collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise. 

Oxford Biomedica, a FTSE4Good constituent, is headquartered in Oxford, UK. It has locations across Oxfordshire, UK and near Boston, MA, US. Learn more at www.oxb.comwww.oxbsolutions.com, and follow us on LinkedInTwitter and YouTube

Life at Oxford Biomedica

We value everyone’s unique contribution, we appreciate everyone’s individuality, and every job matters.

Your contributions are recognised and appreciated. Your work-life balance matters. We recognise, develop and use your strengths. It’s a place where you are valued as a whole person, as an individual and as part of a team.

No matter who you are, or what you do, your work will make a significant difference.

We go the extra mile, every day, because we truly care. We work together as a team to achieve our life changing therapies. Our talented colleagues help to build other people’s futures, so can you. We empower each other to be our best.

We have access to like-minded scientists and engineers, working in the latest technologies.

Our community of experts create new life-saving cures. Shaping the business’ future through collaboration. Our people are on a continuous professional development journey aided by a thought-provoking environment. A place for experts to be stretched, and future experts to be nurtured. We inspire creativity and deliver great science, and so can you.

Our supportive culture invites talent, while creating future innovators.

We’ll give you a place where you can learn, grow and contribute to the future of cell and gene therapy. We create opportunities and invest in our people, promoting ongoing learning.  Our defined career pathways provide opportunities for everyone to achieve their career potential.  We make a difference, and so can you.

Company info
Website
Telephone
+44 (0) 1865 783 000
Location
Windrush Court
Transport Way
Oxford
OX4 6LT
United Kingdom

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