Skip to main content

This job has expired

Scientist 3/4, Translational Science Group (18 month Fixed Term Contract)

Employer
Oxford BioMedica (UK) Limited
Location
Oxford
Salary
Competitive
Start date
17 Jun 2019
Closing date
17 Jul 2019

View more

Discipline
R & D , Scientific
Hours
Full Time
Contract Type
Contract
Experience Level
Experienced (non-manager)

Job Details

Oxford BioMedica is a pioneer of gene and cell therapy and our work is helping to deliver life changing treatments.

Gene and cell therapy is the treatment of disease by the delivery of therapeutic DNA into a patient’s cells, providing long term and potentially curative treatments for a wide range of diseases. With the potential to transform medicine, the sector holds significant promise with the first commercial products now launched and others rapidly approaching the market.

Our recent successes are driving significant growth. As such, we are looking to recruit a Scientist 3/4 to join our Translational Science Group.  The purpose of this role is to monitor the persistence, bio-distribution and shedding of EIAV/HIV based vectors in clinical and non-clinical samples utilising a number of nucleic acid extraction and PCR techniques in accordance with GLP/GCP compliance and drive continuous quality improvements in compliance with GLP/GCP regulations

Key responsibilities and accountabilities:

  • Provide analytical support to the Study Directors (SDs), Principle Investigator (PIs) and Analytical Project Managers (APMs) with the scope to train to become a SD/PI/APM
  • Monitor the biodistribution, persistence and shedding of EIAV/HIV vectors in clinical and non-clinical samples utilising a number of nucleic acid extraction techniques and PCR techniques in accordance with GCLP/GLP compliance
  • Drive continuous quality improvement with the compliance with GLP/GCP regulations
  • Maintain a high standard of data recording and reporting of all results
  • Perform quality control checks on assay packs for a variety of assay types
  • Support the maintenance of GLP compliant facilities, performing general laboratory duties, for example calibration, monitoring and cleaning of equipment
  • Assist with the improvement of current assays and the development and validation of new assays
  • Perform quality control checks on assay packs for a variety of assay types
  • Produce documentation (SOPs, equipment files) to a high standard
  • Contribute to group meetings, presentation of data, suggesting and implementing quality improvements

Key skills and requirements:

  • A minimum of degree level (or equivalent) in an appropriate biological science subject
  • Previous laboratory experience working to GLP / GCP compliance
  • Excellent attention to detail and a meticulous attitude to documentation of data capture
  • Demonstrated ability to work independently as well as in a team setting
  • Excellent time management and organisational skills

Person Specifications:

The Translational Sciences Group is seeking a highly motivated and enthusiastic individual with relevant laboratory experience, preferably in a GLP/GCP environment.  You will have extensive experience in at least two of the following analytics: extraction of nucleic acids from biological samples, qPCR and RT-qPCR, SDS-PAGE, Western blotting, cell culture and be capable of generating robust, accurate and precise results.  You will be able to provide evidence of performing scientific research. You will be well organised and have excellent attention to detail.

No agencies please

Company

Oxford Biomedica is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, Oxford Biomedica has more than 25 years of experience in viral vectors, the driving force behind the majority of gene therapies.  

Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patient’s cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients’ cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).  

Oxford Biomedica collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise. 

Oxford Biomedica, a FTSE4Good constituent, is headquartered in Oxford, UK. It has locations across Oxfordshire, UK and near Boston, MA, US. Learn more at www.oxb.comwww.oxbsolutions.com, and follow us on LinkedInTwitter and YouTube

Life at Oxford Biomedica

We value everyone’s unique contribution, we appreciate everyone’s individuality, and every job matters.

Your contributions are recognised and appreciated. Your work-life balance matters. We recognise, develop and use your strengths. It’s a place where you are valued as a whole person, as an individual and as part of a team.

No matter who you are, or what you do, your work will make a significant difference.

We go the extra mile, every day, because we truly care. We work together as a team to achieve our life changing therapies. Our talented colleagues help to build other people’s futures, so can you. We empower each other to be our best.

We have access to like-minded scientists and engineers, working in the latest technologies.

Our community of experts create new life-saving cures. Shaping the business’ future through collaboration. Our people are on a continuous professional development journey aided by a thought-provoking environment. A place for experts to be stretched, and future experts to be nurtured. We inspire creativity and deliver great science, and so can you.

Our supportive culture invites talent, while creating future innovators.

We’ll give you a place where you can learn, grow and contribute to the future of cell and gene therapy. We create opportunities and invest in our people, promoting ongoing learning.  Our defined career pathways provide opportunities for everyone to achieve their career potential.  We make a difference, and so can you.

Company info
Website
Telephone
+44 (0) 1865 783 000
Location
Windrush Court
Transport Way
Oxford
OX4 6LT
United Kingdom

Get job alerts

Create a job alert and receive personalised job recommendations straight to your inbox.

Create alert