Modelling and Simulation Senior Scientist - Home-based - US / EU
- Employer
- RBW Consulting
- Location
- East-Coast USA
- Salary
- Competitive
- Start date
- 28 Feb 2019
- Closing date
- 30 Mar 2019
View more
- Discipline
- Clinical Research, Clinical Project Manager, Clinical Services, Clinical Trials Manager / Administrator, Study Site Coordinator, Data Management / Statistics, Informatics, Medical Affairs, Medical Advisor, R & D , Biochemistry, Biology, Biotechnology, Pharmacology, Pre - clinical, Scientific
Job Details
I am currently seeking an exceptional Modelling and Simulation Senior Scientist to work with a leading global drug development company. This is a fantastic opportunity to work in a dynamic, flexible role, with the opportunity to work from a home-based position. This opportunity has an added level of flexibility that will enable this position to be based in either EU / US locations.
The Modelling and Simulation Senior Scientist will support projects from early discovery stages through to clinical trials. The successful applicant will develop, implement and validate models using pre-clinical in vitro and in vivo data with the aim to provide a robust prediction of human pharmacokinetics and efficacious dose.
Skills required:
- Excellent understanding of theory, principles and statistical aspects of advanced mathematical modelling and simulation
- Thorough understanding of the basic principles of pharmacokinetics (non-compartmental, compartmental, PBPK) and the use of pre-clinical data for human efficacious dose prediction
- Proficient in the use of software and applications in the area of PBPK / PKPD modelling and simulation
- Proficient knowledge of modelling software, such as GastroPlus, SimCYP, Phoenix, MATLAB, Berkeley-Madonna, R, NONMEM or comparable applications.
- Develop and validate mathematical PK/PD/Biomarker/Efficacy models to elucidate the quantitative PK/PD relationships in pre-clinical species
- Good written and verbal communication skills with the ability to summarise outcomes clearly
I manage a range of other permanent and freelance positions for a broad portfolio of clients (Biotech, CRO and Pharma). If the above role isn’t for you but you’d nevertheless like to discuss your options in the market, I’d welcome a confidential discussion by phone or email. Contact Ian Kulka at +44 (0)1293 584 300 or +1 (617) 982 1238.
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