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Senior Scientist, Cell Technology Group

Employer
Oxford BioMedica (UK) Limited
Location
Oxford, Oxfordshire (GB)
Salary
Competitive
Start date
14 Feb 2019
Closing date
8 Mar 2019

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Discipline
R & D , Scientific
Hours
Full Time
Contract Type
Permanent
Experience Level
Experienced (non-manager)

Job Details

Our recent successes are driving significant growth. As such, we are looking to recruit an experienced scientist to support the development of new technologies for the next generation of gene and cell therapies. The Company has a platform of exclusive and pioneering technologies on which are designed, developed and manufactured unique gene- and cell-based medicines.

A highly motivated individual is sought to work within this team-orientated group. The successful candidates will be involved in developing new technology for gene and cell therapy products.

Key skills and requirements:

  • PhD or equivalent in relevant Bioscience (e.g. immunology, molecular and cellular biology) and have several years’ post-doctoral experience in academia or industry
  • Track record in an area of immunology would be advantageous
  • Excellent lab-based skills with particular emphasis on cell biological techniques including cell culture, cell transfection, viral vector production/purification (especially lentiviral vectors), immunofluorescence and multiparameter flow cytometry
  • Expertise with primary cell culture or organoids would be an advantage
  • Experience of genetic engineering and gene editing e.g CRISPR-Cas9 would be desirable
  • Excellent written and verbal communication skills
  • Excellent organisational and time management skills
  • Good attention to detail
  • Highly motivated
  • Ability to execute projects to aggressive timelines with the ability to adapt to rapid changes in project priorities.

 

Key responsibilities and accountabilities:

  • Development and improvement of lentiviral vector technologies for gene and cell therapy applications
  • Lead/manage research in the group
  • Independently manage daily research activities and support junior members of staff
  • Keep excellent experimental/data records
  • Opportunity for direct line management within the Group.
  • Support other members of the team and the wider Research Group as required

 

Person Specification:

  • Experience in gene or cell therapies preferable but not essential
  • Immunology experience desirable
  • A highly motivated, enthusiastic, positive attitude
  • Ability to demonstrate (by peer-reviewed publications) the ability to work independently, and with a good understanding of the field they are working within
  • Ability to work well in a team setting and when appropriate, ensure others are able to perform the tasks to the benefit of the team objective

Oxford BioMedica is a pioneer of gene and cell therapy and our work is helping to deliver life changing treatments.

Gene and cell therapy is the treatment of disease by the delivery of therapeutic DNA into a patient’s cells, providing long term and potentially curative treatments for a wide range of diseases. With the potential to transform medicine, the sector holds significant promise with the first commercial products now launched and others rapidly approaching the market.

Company

Oxford Biomedica is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, Oxford Biomedica has more than 25 years of experience in viral vectors, the driving force behind the majority of gene therapies.  

Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patient’s cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients’ cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).  

Oxford Biomedica collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise. 

Oxford Biomedica, a FTSE4Good constituent, is headquartered in Oxford, UK. It has locations across Oxfordshire, UK and near Boston, MA, US. Learn more at www.oxb.comwww.oxbsolutions.com, and follow us on LinkedInTwitter and YouTube

Life at Oxford Biomedica

We value everyone’s unique contribution, we appreciate everyone’s individuality, and every job matters.

Your contributions are recognised and appreciated. Your work-life balance matters. We recognise, develop and use your strengths. It’s a place where you are valued as a whole person, as an individual and as part of a team.

No matter who you are, or what you do, your work will make a significant difference.

We go the extra mile, every day, because we truly care. We work together as a team to achieve our life changing therapies. Our talented colleagues help to build other people’s futures, so can you. We empower each other to be our best.

We have access to like-minded scientists and engineers, working in the latest technologies.

Our community of experts create new life-saving cures. Shaping the business’ future through collaboration. Our people are on a continuous professional development journey aided by a thought-provoking environment. A place for experts to be stretched, and future experts to be nurtured. We inspire creativity and deliver great science, and so can you.

Our supportive culture invites talent, while creating future innovators.

We’ll give you a place where you can learn, grow and contribute to the future of cell and gene therapy. We create opportunities and invest in our people, promoting ongoing learning.  Our defined career pathways provide opportunities for everyone to achieve their career potential.  We make a difference, and so can you.

Company info
Website
Telephone
+44 (0) 1865 783 000
Location
Windrush Court
Transport Way
Oxford
OX4 6LT
United Kingdom

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