Clinical Professionals Ltd

Research Scientist - Fermentation

09 Jan 2019
14 Feb 2019
R & D

Our client's class-leading platform enables precise and large-scale identification of gut bacteria associated with health or disease, enabling the design of novel medicines and biomarkers based on live bacteria. In just two years, the company has established itself as an industry leader, having won four awards and recently signed a $534m strategic multi-year deal with a major US Biotech to discover novel biomarkers, targets and medicines in inflammatory bowel disease. The company has a pipeline of live bacterial products for C. difficile, ulcerative colitis and cancer which will be progressed to the clinic.

To support these activities our client is seeking a Research Scientist with expertise in Microbial Fermentation Process development to work in the Preclinical Development Team. This is an exciting opportunity for an enthusiastic individual to be involved at the early stages of this novel area of pharmaceutical medicine.

Role and Responsibilities

The role will be responsible for the development of fermentation processes that grow selected bacteria in sufficient quantities to be processed into a therapeutic product and for the harvesting and preservation techniques that maximise the viability of the organisms. The work will involve close liaison with scientists researching the physiology and function of novel bacteria. There will be an opportunity to both perform experimental work in the companys well-equipped laboratories and to work in collaboration with external contractors.

The major areas of responsibility are:

As part of a team, develop fermentation processes to produce live bacterial therapeutics
Liaise with research microbiologists to understand the physiological requirements of novel gut bacteria
Document experimental work to meet the requirements of appropriate guidelines and regulations
Operate fermenters and carry out downstream processing
Maintain and prepare equipment
Maintain an awareness of new technologies for incorporation into company labs

Candidate Specifications:
Essential requirements for this post include:
A PhD in a relevant discipline (eg: Microbiology or Bioprocess Engineering or a closely related subject) or, a BSc in Microbiology or Bioprocess Engineering and two years of experience in a bioprocess development environment utilising fermentation technology

Desirable requirements for this post include:
Experience of developing manufacturing processes for application in GMP manufacture
Experience in a bioprocess development environment utilising fermentation technology
An ability to design, execute and document experimental activities to the standards required for regulatory filings

The following personal attributes are essential:

An ability to work independently
A natural sense of organisation, team work, as well as sharing know-how and expertise in a multidisciplinary environment
Good presentational skills, both oral and written
Flexibility to work in a new and dynamic company
Candidates must be legally entitled to work in the UK

If this role sounds like it could be of interest to you, or you would like to find out more about the position, client or process, please contact Matt Walsh on 0207 822 1710 or email an up to date version of your CV to

If however, you do not feel that this is the right role for you, please forward these details on as we do have a generous referral scheme in place. Please note, due to the high volume of applications, if you do not receive a response within 48 hours, your application has not been successful on this occasion.

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