Principal Data Scientist Biomarker & Target ID

We have a great Principal Data Scientist for Biomarker & Target Identification role with our #machinelearning #unicorn #biotech client. This is focussed in #precisiononcology

Are you passionate about developing and leading #drugdiscovery projects in #ai and #machine learning in #multi-omics?

This role is perfect for a #principalscientist or #pi who wants to move into a more commercial role working across #multi-modalities leading highly innovative drug discover projects.

Position is ideally based in our client's office in Paris, London, Berlin but we can also consider remote if you are prepared to travel to core team meetings in Paris.

About the role:

As a Lead/ Principal Scientist you will lead high-impact research projects at the interface of machine learning, computational biology, bioinformatics and drug discovery & development.

These projects will be focused on building machine learning models from multimodal data (genomic data, histology, radiology, clinical,...), to identify new biomarkers, therapeutic targets, drug combinations, indications expansions and optimized drug development strategies.

You will be part of the R&D team and will collaborate with scientists and/or external collaborators (academic researchers / pharmaceutical companies) to deliver these research projects centered around specific cancer diseases.

In particular, you will:

• Lead research projects interacting with academic partners and/or pharma (involving publication, mentoring of junior scientists,...) to better understand disease mechanisms, and to generate new hypotheses about potential therapeutic strategies
• Develop internal research projects to advance core scientific methodologies, focusing on the development of methods leveraging multi-modal patient data (multi-omics as well as histology, radiology and clinical data) to improve the precision of biomarker and target identification approaches
• Work in collaboration with other departments to support marketing, business development & communications activities .

Ideal qualifications / experience:

• PhD or MSc in Computational Biology, Bioinformatics, Machine Learning, Computer Science, Statistics or related field with relevant industry or academic experience
• Prior experience in leading large scientific projects with demonstrated ability to write detailed research plans and reports
• Demonstrated ability to lead several scientists to achieve scientific objectives
• Strong programming skills in Python and/or R with demonstrated knowledge of exploratory analysis and data visualisation.
• Expertise working with -omics data, in particular in single cell and spatial omics technologies, with a strong publication record.
• Experience working in target or drug discovery settings is a plus.
• Familiar with machine learning toolkits and concepts e.g. scikit learn, xgboost, cross validation, statistical tests
• Experience with deep learning frameworks such as Tensorflow, PyTorch strongly preferred.
• Team first, highly collaborative mindset.
• Excellent written and oral communication skills. Fluent in English. Fluent in French is a plus.
• Highly organised and meticulous about details; capable of tackling complex problems logically and effectively; fun to work with; honest; excited to work hard in a dynamic, fast-paced environment
• Passionate about the intersections of healthcare and AI
• Proficiency in next-generation sequencing data analysis e.g. RNA-Sequencing, DNA-Sequencing
• Previous experience with target identification approaches in oncology is a big plus

What our client offers:

• Competitive salary & excellent benefits package
• Flexible work organization and access to remote work
• Friendly and informal working environment
• Opportunity to work with an international team with high technical and scientific backgrounds

Contact Gail Kniveton for more information

#precisiononcology #ai #ml #principalscientist #drugdiscovery #precisionmedicine #genomics #multi-omics