Associate Scientist-Downstream Process Development

Proclinical Staffing
Massachusetts, Worcester, USA / USA, Massachusetts, Waltham / Boston, Massachusetts, USA
Highly Competitive Salary
Start date
22 Nov 2022
Closing date
6 Dec 2022

View more

Manufacturing, Process, R & D , Scientific
Full Time
Contract Type
Experience Level
Experienced (non-manager)
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Job Details

Proclinical is seeking an Associate Scientist-Downstream Process Development for a leading biopharmaceutical company located in Waltham, MA.

This scientist will work collaboratively with other members of the PD and analytical development teams to advance these objectives. The downstream PD team operates with the mission to develop and transfer robust, scalable, cost effective viral vector purification and formulation processes and drive development and implementation of innovative internal technology platforms.

Job Responsibility:

  • Design and perform world-class downstream technology protocols from bioreactor recovery, affinity-column purification, impurity removal, particle enrichment strategies, ultrafiltration and diafiltration (UF/DF), and sterile filtration
  • Advance current methods and develop new methods to purify viral vectors, leaving no stone unturned
  • Collaborate with suppliers and vendors on design, procurement, and testing of PD equipment
  • Ensure documentation and data management best practices are followed, reviewing documentation as needed
  • Support collaborations with partners, clients, technology developers, and suppliers

Skills and Requirements:

  • Bachelor's degree with 4+ years or master's degree with 2-4 years of relevant experience in downstream process development
  • Background in the development of column purification, UF/DF, sterile filtration, product recovery strategies
  • Understanding of downstream process development, scale up and technology transfer
  • Excellent written and verbal communication skills
  • Experience applying scientific principles and concepts to potential innovative platforms and disruptive technologies
  • Experience with process characterization and Design of Experiments (DOE)
  • Understanding of early and late-stage process development
  • Embodies the companies phenotypes of grit, rigor, service, EQ+IQ, builder mentality, velocity, and ownership
  • Intellectually curious, flexible, able to contribute at a very high level, as well as possessing a hands-on manner, when necessary
  • Collaborative style, with an ability to build consensus among both internal and external stakeholders

If you are having difficulty in applying or if you have any questions, please contact Miranda Gilmer at (+1) 570-277-7065 or

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies.

Proclinical Staffing is an equal opportunity employer.



At ProClinical we have one aim: to support life science companies in the many challenges they face while combatting unmet medical need worldwide.

Ageing populations, rare diseases, epidemics and the millions of patients without access to medication are just a few of the pressing issues that life science companies contend with. The industry is under increasing pressure to develop new and innovative ways to save and improve patients’ lives. 

ProClinical’s mission is to support their work by connecting life science companies with the highly skilled professionals they need to continue innovating. 

Internal recruitment and HR teams often struggle to continuously source skilled, experienced professionals to fill highly-specialised and niche roles. ProClinical combines a deep understanding of the industry with extensive candidate networks to provide both a technical and cultural fit for our life science partners.


Find Us
0800 988 4437
Eldon House
Eldon Street
United Kingdom

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