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Senior Principal Scientist - Pharmacometrics

Boehringer Ingelheim
Biberach, Germany
Start date
26 Sep 2022
Closing date
25 Oct 2022

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R & D
Full Time
Contract Type
Experience Level
Experienced (non-manager)
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Job Details


At Boehringer Ingelheim we develop breakthrough therapies and innovative healthcare solutions in areas of unmet medical need for both humans and animals. As a family owned company, we focus on long-term performance. We believe that, if we have talented and ambitious people who are passionate about innovation, there is no limit to what we can achieve; after all, we started with just 28 people. Now, we are powered by 50,000 employees globally who nurture a diverse, collaborative and inclusive culture


Are you passionate about applying your pharmacometric skills, strategic thinking, and practical experience in data science? Would you like to join cross-functional clinical development teams, and do you feel like expanding your influence and deepening your knowledge in data science approaches beyond pharmacometrics?

You will also have the exciting prospect of acting as a Data Science Lead (DSL) in clinical development project teams to fulfill our vision of turning data into knowledge. As DSL, you’ll have the chance to shape and contribute to projects already prior to first-in-man clinical trials.

We are offering an exciting opportunity in our global Translational Medicine & Clinical Pharmacology (TMCP) department located in Biberach an der Riss ( ), our biggest R&D site, or at our headquarters in Ingelheim.

If you would like to learn more on the vision and mission of our TMCP Data Science department, please see below in TMCP Data Science Section.

Tasks and responsibilities

  • As a Senior Principal Scientist in Pharmacometrics, you will develop the pharmacometric strategy and identify opportunities where pharmacometrics and other advanced data analytic approaches can further the understanding of pharmacological activity, efficacy and safety of a drug.
  • You will join cross-functional clinical development teams as a Data Science Lead (DSL) where you will work in close alignment with other team members and data science subject matter experts and are responsible for:
    • advising clinical development teams on opportunities and limitations of Data Science approaches (e.g. pharmacometrics, computational biology, systems pharmacology, descriptive analytics)
    • developing and aligning the TMCP data and data analysis strategy in close alignment with other DS experts within our department
    • complex clinical development projects up to submission representing pharmacometrics at important regulatory meetings such as advisory boards
  • Furthermore, you will be responsible for the planning and execution of relevant pharmacometric analyses to support internal decision making, disease understanding and successful approval.
  • You will ensure the timely delivery of analysis-related documentation (e.g., dataset specification, analysis plans, and reports) and documents where you are co-author (e.g., clinical development plans).
  • Moreover, you will continuously evaluate or develop, implement, and promote innovative pharmacometric methodologies, approaches, (software) tools and related business processes.
  • You will provide consultancy and expert advice for other scientists and stakeholders across therapeutic areas as an internally and externally recognized scientist.
  • You will lead and/or contribute to internal and external initiatives/working groups (e.g. focus groups in your therapeutic area of expertise, across department initiatives, process harmonization, IMI calls, ISoP groups, Open Systems Pharmacology), organize and manage projects with external organizations and establish and maintain contacts to key opinion leaders in the field of pharmacometrics and data science in general.


We expect a strong team player, who is able to successfully act in the global and remote context. Good interpersonal skills with the ability to interact effectively with people, internally and externally (e.g., CROs, experts, management) and the ability to pro-actively identify issues and solutions and to interact with internal and external bodies on TMCP data science issues are a pre-requisite.
  • PhD. or master’s degree in Medicine, Pharmacometrics, Clinical Pharmacology, Pharmacy, Mathematics, Biology, Statistics or relevant area of focus
  • Long-standing experience in Pharmacometrics/Data Science in the pharmaceutical industry, regulatory agencies, CRO or academia with relevant experience in working in clinical development teams
  • Comprehensive knowledge in applying PMx software (e.g., NONMEM, Monolix, R, PBPK software) and approaches (e.g. population pharmacokinetics, pharmacokinetics/pharmacodynamics, exposure response, disease progression modeling, model-based meta-analysis as well as PBPK)
  • In-depth knowledge in other data science fields, clinical pharmacology, clinical drug development, MID3, and regulatory guidelines

TMCP Data Science

Within TMCP Data Science we are focusing on improving disease, biomarker and drug understanding through modern data science approaches, including bioinformatics, systems pharmacology, pharmacometrics, data enablement and data engineering.

To implement our vision of turning data into knowledge, we utilize our scientific expertise in key data science approaches and act as Data Science Leads in development project teams. In this role you will be a main contact for data science related questions supported by the whole TMCP Data Science group. You will join the clinical development team approximately two years before first-in-man clinical trials and support projects until successful regulatory approval and beyond.

We inspire and empower data scientists within TMCP to shape the future of Data Sciences at BI and value a culture of sharing knowledge, pro-active contributions, and feedback combined with a positive “how to” attitude also in challenging situations. Within TMCP Data Sciences you will have the opportunity to actively contribute or lead internal and external working groups/initiatives focusing on e.g. disease strategies, innovative methods, standardization and processes. Thus, you will have a major impact on our future clinical drug development programs, thereby actively contributing to the availability of breakthrough therapies that will increase human health.

Seize the opportunity and apply as Senior Principal Scientist in Pharmacometrics at Boehringer Ingelheim.


We will continue to hire talented people and we look forward to receiving your applications. As a result of COVID-19, we have introduced alternative working arrangements to ensure that our employees can stay safe and healthy, because the health of our employees is among our top priorities. At all company locations, we work remotely whenever possible. Additionally, we are now hosting virtual video interviews for applicants. During the limited in-person interviews we still have during this time, we pay special attention to distance and the hygiene rules recommended by the Robert Koch Institute. New employees who do not start on site in production or the laboratories are sent the necessary IT equipment, our Welcome Days take place online, and we plan to conduct their onboarding training virtually whenever possible.


This is where you can grow, collaborate, innovate and improve lives.

We offer challenging work in a respectful and friendly global working environment surrounded by a world of innovation driven mindsets and practices. In addition, learning and development for all employees is key, because your growth is our growth. We also offer a competitive salary, generous amount of vacation time, and numerous benefits towards your wellness & financial health and work-life balance. Plus, an onsite gym (Ingelheim), in-house doctor and best-in-class cafeterias and coffee bars to keep you energized and healthy. To learn more about what benefits could be waiting for you, please visit our Career area.

Want to learn more about us? Visit

Boehringer Ingelheim is an equal opportunity global employer who takes pride in maintaining a diverse and inclusive culture. We embrace diversity of perspectives and strive for an inclusive environment, which benefits our employees, patients and communities. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or national origin.


Please contact our Recruiting EMEA Team, Tel: +49 (0) 6132 77-173173

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With 47,700 employees in 103 countries, Boehringer Ingelheim is one of the world's top 20 pharmaceutical companies. Since its foundation in 1885, the family-owned company has been pursuing an ambitious goal: to research and develop innovative pharmaceuticals that improve the health and quality of life of humans and animals alike

Find Us
Binger Straße 173
Ingelheim am Rhein
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