Job description:
 

Our employees are able to develop their careers in exciting new medical technologies, and so can you.

Oxford Biomedica’s (OXB) Cell Engineering Group (CEG) is part of the Platform Research Department and its primary function is to develop stable cell lines, which will ultimately be used for the production of lentiviral vectors (LVs) for therapeutic use.

CEG is seeking to recruit an experienced scientist, for an eighteen month fixed term contract, who will be required to plan, execute and report experiments as well as supporting other members of the team as needed. The successful candidate will have skills and experience with tissue culture, cell line development and molecular biology. Experience with any of the following would be an advantage: LV production, gene-editing techniques or NGS platforms and bioinformatics.

Your responsibilities in this role would be:

• Involvement in Cell Engineering project activities, may include, plasmid development, cell line development, analytical assays, gene editing, LV production, LV production in bioreactors, LV characterisation, NGS and laboratory automation
• Design and conduct experiments /investigations in accordance with correct methodologies and procedures under the direction of Principal and Senior Scientists
• Maintain a high standard of record keeping and documentation of experiments and investigations to ensure that information is captured clearly and timely
• Analyse and interpret data for documenting and reporting at internal meetings and  client meetings
• Prepare written reports to a high standard
• Conduct research and technical support of the highest quality in line with role specific activities
• Share scientific knowledge through regular team/department meetings and presentations
• May be responsible for maintenance of a laboratory area and/or important equipment
• Maintain excellent laboratory citizenship
• Contribute to the efficient and safe operation of the laboratory

To be successful in this role, you will have the following skills and experience:

• BSc, MSc in an applicable Bioscience with an appropriate level of relevant experience

• Experience in general cellular and molecular biology techniques
• Practical experience with several of the following: tissue culture, flow cytometry, nucleic acid extractions, qPCR and plasmid cloning.
• Experience with LV production is desirable
• It would be an advantage, but not essential, to have demonstrated experience with one or more of the following - Gene editing, nanopore/NGS sequencing platforms and/or bioinformatic analysis, Python.
• Knowledge in Virology and Gene Therapy would be an advantage.

• Attention to detail.
• Good organisational and time management skills.
• Able to prioritise workloads and work under pressure.
• Highly motivated and enthusiastic.
• Demonstrated ability to work well in a team

Do you want to feel inspired every day? We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment and team work, and so can you.

Collaborate. Contribute. Change lives

No agencies please

We offer:

We are a pioneering gene therapy business, and our mission is delivering life changing gene therapies to patients. We work together, motivated to make a difference, and so can you.

We are pioneers; no one else does what we do.

Gene therapy is the treatment of disease by the delivery of therapeutic DNA into a patient’s cells. It is transforming medicine as we know it, long term and potentially curative treatments for a wide range of diseases are now possible.

We are at the forefront of this exciting area. We have a strong reputation in gene therapy, with world leading expertise in lentiviral vectors. We have a leading, integrated platform of exclusive technologies to design, develop and bioprocess unique gene based medicines, both in house and with partners.

We drive credible science to realise incredible results.

Whether you’re motivated by the discovery and development of product candidates within Research, or by cutting edge tools and technologies including AI and automation of our contract development and manufacturing organisation, we can offer you a career like no other. We are excited about our future. Join us and change lives.