Head of Clinical Pharmacology

Hobson Prior have an exciting position for a Head of Clinical Pharmacology to join a global biotechnology organisation whose mission is to make a difference in AML patient care.

Please note that to be considered for this role you must have the right to work in this location.

Key Responsibilities:

• Define and lead the Clinical Pharmacology / PKPD strategy and development program in collaboration with in-house expert functions and external consultants.
• Ensure consistency of the nonclinical ADME package (including bioanalytical methods) with the Clinical Pharmacology strategy for current and potential new indications.
• Provide expert scientific input on pharmacodynamic endpoints and biomarkers pertinent to the underlying pathophysiology of immunology-related diseases or compound mechanism of action.
• Design and interpret Clinical Pharmacology studies to evaluate potential effects of intrinsic and extrinsic factors on PK and PD.
• Be accountable for Clinical Pharmacology / PKPD and nonclinical ADME deliverables and registration packages by coordinating in-house or external activities.
• Liaise with key expert functions and management to identify potential project hurdles, provide solutions and contribute to contingency plans.
• Be responsible for the budget and resources allocated to Clinical Pharmacology / PKPD and nonclinical ADME activities.
• Contribute to the evaluation of licensing-in opportunities and patent filings.
• Provide technical and operational support for PKPD and pharmacometrics database management in collaboration with internal experts and external providers.
• Responsible for the timely and effective communication of strategy and results to Project Teams and Management.
• Responsible for external communication of Clinical Pharmacology / PKPD and ADME results to congresses and scientific meetings.

Requirements:

• PhD/PharmD/MD, or equivalent.
• At least 10 years' experience as a clinical pharmacologist or PKPD project leader in a cross-functional clinical development team in big pharma or biotech.
• Hands on expertise in PKPD analysis and sound understanding of pharmacometrics.
• Strong scientific expertise in immunology with an excellent understanding of immuno-pathophysiological processes. Prior experience with therapies in hematology is a plus.
• Experience in managing CROs and external service providers.
• Excellent understanding of translational science, including biomarker development and validation.
• Proven track record in leading a scientific team(s) and direct and/or indirect people management experience in big pharma companies.
• Extensive experience in the preparation of clinical pharmacology registration documents.
• Proven track record in direct interaction with health authorities.

Apply now:

If you are interested in learning more or applying to this exciting opportunity then please click "Apply" and upload a copy of your CV. Alternatively, for further details or to talk directly to a life sciences recruitment specialist directly, please select "Contact me" at the top of this page.

Hobson Prior is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Hobson Prior is acting as an Employment Agency in relation to this vacancy.