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Principal Scientist, Analytical Development

Employer
Oxford BioMedica (UK) Limited
Location
Oxfordshire
Salary
GBP - Unavailable
Start date
12 Jul 2021
Closing date
11 Aug 2021

View more

Discipline
R & D , Scientific
Hours
Full Time
Contract Type
Permanent
Experience Level
Management

Job Details

Job description:
 

We drive credible science to realise incredible results, and so can you.

 

We are currently recruiting for a highly motivated Principal Scientist to join the Analytical Development Group.  The purpose of this role is to provide first rate analytical development for external partnerships and for the company’s portfolio of cell and gene therapies. The group functions in a multi-disciplined innovative environment whilst also adhering to internal and external quality systems. ADG is part of the Research Department but works closely with manufacturing, clinical and analytical services at all stages of development. The team is responsible for assay development and subsequent qualification and validation to support the GMP manufacturing process and early phase development through to commericalisation of products.

 

Your responsibilities in this role would be:

 

  • Have responsibility for the research, development and implementation of new and existing assays to support internal and external cell and gene therapies programmes
  • Support the development of Oxford BioMedica’s pipeline and work closely with Project Management
  • Line management of junior scientists
  • Troubleshoot assay performance issues as and when required
  • Drafting and preparation of standard operating procedures for new assays and support drafting of regulatory modules
  • Assist in the scheduling, management and execution of the ADG to deliver programs of work
  • Act as project manager for validation, qualification and transfer studies both internally and with external partnerships.
  • Training members of the Analytical Services Group (ASG) to perform newly developed and validated assays

 

To be successful in this role, you will have the following skills and experience:

 

  • BSc Degree in Life Sciences/Science/Analytical Science
  • Strong scientific background in molecular biology or biochemistry
  • Experience in line management of a team of scientists
  • Experience with qPCR and protein analysis is essential
  • An understanding of lentiviral vectors and gene therapy is essential
  • Previous experience with assay development or validation in an industrial setting
  • Use of statistics as applied to assay validation
  • The ability to train others in the conduct of analytical techniques
  • Demonstrated ability to work independently as well as in a team
  • Good written and verbal communication skills
  • Ability to undertake projects to agreed timelines and adapt to rapid changes in project priorities

 

Do you want to feel inspired every day? We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment and team work, and so can you.

 

Collaborate. Contribute. Change lives

 

No agencies please

 


We offer:

 

 

 

We are committed to offering highly competitive reward packages for all our staff. That’s why, every year, we benchmark our salaries and benefits against the local pharmaceutical market – by that, we mean that we compare our packages with those of other major companies in the London, Oxford, Cambridge areas.

We’re looking for highly skilled, focused individuals to help us deliver life-changing therapies to patients. It’s no mean feat, and we have to work together to make this happen.

Along the way, you’ll have a rich variety of opportunities to really develop your career. We’ll also give you a generous set of employee benefits and a competitive salary.

 

 

Company

Oxford Biomedica is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, Oxford Biomedica has more than 25 years of experience in viral vectors, the driving force behind the majority of gene therapies.  

Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patient’s cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients’ cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).  

Oxford Biomedica collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise. 

Oxford Biomedica, a FTSE4Good constituent, is headquartered in Oxford, UK. It has locations across Oxfordshire, UK and near Boston, MA, US. Learn more at www.oxb.comwww.oxbsolutions.com, and follow us on LinkedInTwitter and YouTube

Life at Oxford Biomedica

We value everyone’s unique contribution, we appreciate everyone’s individuality, and every job matters.

Your contributions are recognised and appreciated. Your work-life balance matters. We recognise, develop and use your strengths. It’s a place where you are valued as a whole person, as an individual and as part of a team.

No matter who you are, or what you do, your work will make a significant difference.

We go the extra mile, every day, because we truly care. We work together as a team to achieve our life changing therapies. Our talented colleagues help to build other people’s futures, so can you. We empower each other to be our best.

We have access to like-minded scientists and engineers, working in the latest technologies.

Our community of experts create new life-saving cures. Shaping the business’ future through collaboration. Our people are on a continuous professional development journey aided by a thought-provoking environment. A place for experts to be stretched, and future experts to be nurtured. We inspire creativity and deliver great science, and so can you.

Our supportive culture invites talent, while creating future innovators.

We’ll give you a place where you can learn, grow and contribute to the future of cell and gene therapy. We create opportunities and invest in our people, promoting ongoing learning.  Our defined career pathways provide opportunities for everyone to achieve their career potential.  We make a difference, and so can you.

Company info
Website
Telephone
+44 (0) 1865 783 000
Location
Windrush Court
Transport Way
Oxford
OX4 6LT
United Kingdom

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