Simbec Orion Group Ltd

Trainee Research Scientist - 12 Month Fixed Term Contract

Location
Merthyr Tydfil, Wales
Salary
Competitive
Posted
18 Jun 2021
Closes
07 Jul 2021
Ref
VA168
Discipline
R & D , Laboratory
Hours
Full Time
Contract Type
Permanent
Experience Level
Graduate
Simbec-Orion is a responsive and agile full-service CRO, with wide therapeutic experience and specialist expertise in clinical pharmacology, oncology and rare diseases. Perfectly structured, we provide full-service clinical development solutions for small and mid-size drug developers - headed up by a centralised leadership team.

With a focus on tailormade and scalable solutions, we'll adapt our delivery style, communications and operations to suit the demands of the project, helping clients achieve their clinical and commercial objectives. Because our goal is the same as theirs; to improve patients' lives.

Summary of the Position:

We are looking for a Trainee Research Scientist to join our Laboratory Services department on a 12 month fixed term contract.

You will works on projects to analyse drugs, metabolites, and other analytes in biological fluids and pharmaceutical preparation, primarily using LC-MS-MS techniques. The role will be laboratory-focused, participating in extraction methods and subsequent LC-MS-MS or ELISA analysis while maintaining meticulous, contemporaneous data recording. You will ensure compliance with regulatory good practice and guidance requirements within set timeframes.

Key Accountabilities:
  • Ensure that work performed adheres to good practice regulations and guidelines.
  • Document all procedures undertaken in a clear, accurate and contemporaneous manner and apply Quality Control (QC) procedures to ensure their accuracy.
  • Communicate the status of work being performed with the assigned Principal Scientist and other team members.
  • Prepare chemicals, reagents, solutions and subsequently process samples generated in a clinical study for routine assay procedures in line with Standard Operating Procedures (SOPs) and Working Instructions(WI).
  • Schedule and run samples using Analyst software, i.e. the routine processing of analytical batches using LC-MS-MS techniques.
  • Schedule and run samples using Gen5 software, i.e. the routine processing of analytical batches using Elisa techniques.
  • Assist in the development of methods of analysis to deliver fully validated assays.
  • Assist with producing relevant documentation (protocols, procedures, validation/study reports, SOP's, CAPA's, file notes) and ensuring they are delivered to the client and archived within expected timeframes.
  • Carry out various general laboratory duties to ensure the efficient operation of the laboratory, such as logging of solvents, database maintenance and waste management.
  • Maintain personal training records to demonstrate competency.

Minimum Requirements:

Essential:
  • Science Degree or working towards a Science degree
  • Experience in working in a laboratory environment
  • Good Organisation Skills with the ability to prioritise work
  • Good general laboratory skills with the ability to use general laboratory equipment such as pipettes, centrifuges, and balances
  • Proficient in using Microsoft Office for documenting and analysing, and reporting data
  • Ability to document laboratory information accurately in a contemporaneous manner
  • Good Communication skills
  • Ability to work to tight deadlines and within constraints

Desirable:
  • BSc in Chemistry or related analytical degree
  • Previous experience in working in a regulated environment (MHRA GCP for labs)
  • Strong attention to detail, proven ability of managing multiple sample analyses
  • Ability to set up and use HPLC system
  • Ability to use analytical systems such HPLC/LC-MS-MS
  • Previous experience of working with LIMS systems
  • Ability to document laboratory information to a GXP standard, including preparation of analytical reports
  • Ability to perform quality control processes
  • Track record of working within a team environment


Simbec-Orion is an equal opportunity employer. Simbec-Orion will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.