Translational Medicine & Biomarker Lead - Precision Medicine

Germany (DE)
On application
27 Apr 2021
27 May 2021
Full Time
Contract Type
Experience Level
Experienced (non-manager)

Senior/Principal Translational Medicine & Biomarker Lead - Precision Medicine

Are you an expert in Precision Medicine, Biomarkers or Translational Medicine? Do you have extensive experience in Companion Diagnostic (CDx) as well as clinical drug development, and a deep knowledge of Oncology and other relevant disease areas?

We are currently seeking a TMCP Precision Medicine Lead for the implementation of Precision Medicine/CDx concepts in drug development programs to be based in Germany.

You will join a global organisation that builds understanding of diseases and drugs by developing and applying innovative translational strategies (including biomarkers, clinical pharmacology, pharmacometrics and digital approaches) across the entire clinical development pipeline.

Tasks and Responsibilities

  • Advise project teams on Precision Medicine/CDx strategies, e.g. regarding patient selection strategies, clinical trial design and identification & application of biomarkers predictive for drug response from a CDx perspective.
  • Be  accountable for the successful implementation of CDx in drug development programs to ensure timely submission of drug and associated CDx test in close collaboration with external CDx partners as well as with internal functions
  • Support clinical teams regarding CDx in internal decision-making committees and in strategic discussions, including agency meetings.
  • Provide internal advice and support through the CDx Center to enable decision making regarding appropriate CDx opportunities.
  • Represent the company in Joint Project teams with external CDx partners.
  • Support qualification and management of third party laboratories and IVD partners, support CDx provider audits to ensure third party QC/QA and regulatory compliance.
  • Contribute to early and late stage CDx-related topics in in-licensing opportunities, incl. due diligence and deal execution.
  • Monitor the external CDx landscape for emerging opportunities, technologies and trends and changes in regulation/legislation.


  • MD/ PhD in Life Sciences (focus on Precision Medicine/CDx)
  • Several years of working experience in the development and implementation of biomarker/CDx concepts in a pharmaceutical or diagnostic company
  • Expert-level knowledge and experience in Precision Medicine, CDx and clinical drug development, as well as a clear understanding of the applicable regulatory requirements
  • Profound disease-area knowledge (in particular Oncology) with strong scientific knowledge of the pathophysiology and the main therapeutic modalities currently approved or in clinical development is advantageous
  • Personal track record in the implementation of biomarkers/CDx assays in drug development with an understanding of the clinical application of such markers, their evaluation and analysis, and the linkage between the biomarker and clinical endpoints
  • The ability to build relationships with internal and external experts and opinion leaders

Apply for Translational Medicine & Biomarker Lead - Precision Medicine

Already uploaded your CV? Sign in to apply instantly


Upload from your computer

Or import from cloud storage

Your CV must be a .doc, .pdf, .docx, .rtf, and no bigger than 1MB

4000 characters left

Marketing Communication

We'd love to send you information about Jobs and Services from by email.

All emails will contain a link in the footer to enable you to unsubscribe at any time.

When you apply for a job we will send your application to the named recruiter, who may contact you. By applying for a job listed on you agree to our terms and conditions and privacy policy. You should never be required to provide bank account details. If you are, please email us.

Similar jobs

Similar jobs