Genomics Lab Head (897395-GBA)

Location
Canton of Basel-Stadt (CH)
Salary
Competitive
Posted
27 Apr 2021
Closes
05 May 2021
Hours
Full Time
Contract Type
Permanent
Experience Level
Experienced (non-manager)

Our client, an innovative and dynamic bio-pharmaceutical company headquartered in Switzerland, covering multiple therapeutic areas, committed into delivering products on the market over the next 5 years, is looking a Lab Head Genomics for a permanent position based in Basel area.

The ideal candidate should have a PhD in a life sciences discipline and 5+ years postdoctoral experience in the field of gene expression and/or NGS analysis proven by a strong publication record.

 

Main Responsibilities:

  • Explore, pilot, and implement established NGS protocols to support projects.
  • Evaluate emerging NGS technologies and use industry networks to pragmatically select and pilot these technologies.
  • Champion genomics in all its facets by active contributions to team and management meetings
  • Providing leadership to the existing genomics platform and its lab members.
  • Active representation of the biomarker group, particularly the genomics capabilities in selected R&D teams.
  • Characterization of clinical translation through integrated analysis of animal models and clinical samples.
  • Driving the exploration of biomarkers and discovery of novel drug targets.
  • Monitor and improve the effectiveness of Translational Biomarker strategy with other functions
  • Performing multivariate biomarker data analysis for several projects in close collaboration with functions in and outside the Translational Biomarker Group, putting experimental results into a biological context using internal and external knowledge databases.

 

 

Qualifications and Experience:

  • Relevant Swiss working/residency permit or Swiss/EU-Citizenship required.
  • PhD in a life sciences relevant discipline
  • Min 5 years postdoctoral experience in the field of gene expression and/or NGS analysis
  • Experience in a pharmaceutical R&D environment and demonstrated experience in the clinical implementation of genomics, e.g., diagnostics or clinical trials would be an advantage.
  • Line management experience (supervision of associates minimally at the MSc level will be considered).
  • Experience with Illumina-based high throughput sequencing applications for the profiling of gene expression and targeted assays.
  • Thorough understanding of strengths and limitations of current (single cell /) sequencing technologies to appropriately advise on the design of complex experiments in disease models that mutually leverage the groups’ multi-omics approaches (including sequencing, mass spectrometry, flow- and cytokine profiling).
  • Expert knowledge in genomics information resources and more advanced pathway / biological network and multivariate analyses.
  • Familiar working within a UNIX environment. relevant experience in data analysis, use of R/Bioconductor and dissemination of results by reports in markdown or shiny apps.
  • Full professional proficiency in English.