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Scientist III, Analytical, Process R&D

Employer
Oxford BioMedica (UK) Limited
Location
Oxfordshire
Salary
Competitive
Start date
14 Apr 2021
Closing date
20 Apr 2021

View more

Discipline
R & D , Scientific
Hours
Full Time
Contract Type
Permanent
Experience Level
Experienced (non-manager)

Job Details

Our employees are able to develop their careers in exciting new medical technologies, and so can you.

Oxford Biomedica’s Process R&D team consists of experienced scientists and engineers that have extensive expertise in all aspects of upstream and downstream development.  PR&D take processes from the laboratory “bench” scale and apply process expertise and engineering fundamentals for delivery to Manufacturing.

We are currently recruiting for a Scientist III, Analytical to join the team.  The purpose of this role is to plan, execute and report relevant investigations, and to support other members of the Group as needed to aid the Group Leader in meeting Group/Department objectives.

Your responsibilities in this role would be:

  • Perform analytical assays to support upstream and downstream process development activities, to inform process understanding and to deliver process characterisation activities.
  • Learn and implement laboratory techniques and demonstrate excellent levels of accuracy and quality when carrying out analytical analyses.
  • Carry out multiple laboratory-based assays each week and complete the data processing for these assays in a timely manner.
  • Contribute to trouble shooting and technical investigations.
  • Contribute to both departmental and company initiatives/projects.
  • Ensure a high standard of record keeping and documentation of experiments and investigations
  • Accountable for own performance in alignment with group objectives and deadlines.
  • Familiar with the principles of experimental design and implementation.
  • Presentation of scientific data at internal meetings.
  • Contribute to the writing, revision and review SOPs and technical reports.
  • Joint responsibility for maintenance and compliance of a GxP laboratory area and GxP “housekeeping” procedures.

To be successful in this role, you will have the following skills and experience:

  • BSc or MSc (or equivalent) in a relevant Bioscience with an appropriate level of relevant experience.
  • Laboratory technical experience with desirable experience in cell culture, qPCR, molecular biology and/or HPLC
  • Knowledge of general cellular and molecular biology laboratory and analytical techniques
  • An understanding of viral vector analytical principles and processes.
  • Practical experience in a range of bioprocess analytical techniques, such as but not limited to, cell-based assays, flow cytometry, nucleic acid extractions, qPCR, SDS PAGE, Western blot analysis, ELISA, and HPLC.
  • An awareness of basic biopharmaceutical process development activities.
  • Competency in data capture and reporting.
  • Aseptic technique.
  • Have some knowledge of the literature in defined project area.
  • Capable of following company standard operating procedures and requirements.
  • Understanding of regulatory requirements e.g. GMP, GLP, GCP and/or Validation and Quality Management systems.

In addition, desirable skills include:

  • Biotechnology industry experience in analytics, biological research and development or equivalent experience gained elsewhere.
  • Experience with cell culture and downstream processing techniques.
  • Understanding of the Quality management reporting structure/responsibilities within OXB.
  • Familiar with the regulatory requirements for analytical work (e.g. product specifications, stability testing guidelines etc).

Do you want to feel inspired every day? We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment and team work, and so can you.

Collaborate. Contribute. Change lives

No agencies please

Company

Oxford Biomedica is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, Oxford Biomedica has more than 25 years of experience in viral vectors, the driving force behind the majority of gene therapies.  

Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patient’s cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients’ cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).  

Oxford Biomedica collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise. 

Oxford Biomedica, a FTSE4Good constituent, is headquartered in Oxford, UK. It has locations across Oxfordshire, UK and near Boston, MA, US. Learn more at www.oxb.comwww.oxbsolutions.com, and follow us on LinkedInTwitter and YouTube

Life at Oxford Biomedica

We value everyone’s unique contribution, we appreciate everyone’s individuality, and every job matters.

Your contributions are recognised and appreciated. Your work-life balance matters. We recognise, develop and use your strengths. It’s a place where you are valued as a whole person, as an individual and as part of a team.

No matter who you are, or what you do, your work will make a significant difference.

We go the extra mile, every day, because we truly care. We work together as a team to achieve our life changing therapies. Our talented colleagues help to build other people’s futures, so can you. We empower each other to be our best.

We have access to like-minded scientists and engineers, working in the latest technologies.

Our community of experts create new life-saving cures. Shaping the business’ future through collaboration. Our people are on a continuous professional development journey aided by a thought-provoking environment. A place for experts to be stretched, and future experts to be nurtured. We inspire creativity and deliver great science, and so can you.

Our supportive culture invites talent, while creating future innovators.

We’ll give you a place where you can learn, grow and contribute to the future of cell and gene therapy. We create opportunities and invest in our people, promoting ongoing learning.  Our defined career pathways provide opportunities for everyone to achieve their career potential.  We make a difference, and so can you.

Company info
Website
Telephone
+44 (0) 1865 783 000
Location
Windrush Court
Transport Way
Oxford
OX4 6LT
United Kingdom

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