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Scientist III, Vector Engineering Group

Employer
Oxford BioMedica (UK) Limited
Location
Oxfordshire
Salary
Competitive
Start date
2 Mar 2021
Closing date
30 Mar 2021

View more

Discipline
R & D , Scientific
Hours
Full Time
Contract Type
Permanent
Experience Level
Experienced (non-manager)

Job Details

Our employees are able to develop their careers in exciting new medical technologies, and so can you.

We are currently recruiting for a Scientist III to join the Vector Engineering team.  The purpose of this role is to provide laboratory-based project support to a number programmes being progressed by the team.

Your responsibilities in this role would be:

  • Culture and maintenance of mammalian cells, molecular biology (including cloning, qPCR, SDS-PAGE/immunoblotting), viral vector production, and flow cytometry assays
  • To undertake laboratory projects under the supervision of senior scientists within the Vector Engineering group with the aim of advancing lentiviral vector design
  • Technically support long-term projects within the Vector Innovation Team and wider Vector Engineering and Platform Research Groups as required
  • Conduct experiments /investigations in accordance with correct methodologies and procedures under the direction of the Group Lead/Principal Scientist
  • Record keeping and documentation of experiments and investigations
  • May be responsible for maintenance of a laboratory area and/or important equipment

To be successful in this role, you will have the following skills and experience:

  • Recent MSc Degree in an appropriate discipline (Biology, Biochemistry, Virology) or BSc degree with relevant post-qualification experience in an academic or industrial setting

Essential Requirements

  • Must have experience with mammalian tissue culture
  • Experience in common molecular biology techniques such as PCR and DNA cloning
  • Experience with flow cytometry

 Highly desirable

  • Experience with virus culture and/or handling viral vectors
  • Experience with primary cell cultures, e.g. PBMCs
  • Experienced in the use of automated liquid handlers
  • Experienced in quantitative PCR methodologies such as q(RT)-PCR, ddPCR
  • Experience with next-generation sequencing technology and data handling
  • Interest and enthusiasm for the gene therapy field

Do you want to feel inspired every day? We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment and team work, and so can you.

Collaborate. Contribute. Change lives

No agencies please

Company

Oxford Biomedica is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, Oxford Biomedica has more than 25 years of experience in viral vectors, the driving force behind the majority of gene therapies.  

Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patient’s cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients’ cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).  

Oxford Biomedica collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise. 

Oxford Biomedica, a FTSE4Good constituent, is headquartered in Oxford, UK. It has locations across Oxfordshire, UK and near Boston, MA, US. Learn more at www.oxb.comwww.oxbsolutions.com, and follow us on LinkedInTwitter and YouTube

Life at Oxford Biomedica

We value everyone’s unique contribution, we appreciate everyone’s individuality, and every job matters.

Your contributions are recognised and appreciated. Your work-life balance matters. We recognise, develop and use your strengths. It’s a place where you are valued as a whole person, as an individual and as part of a team.

No matter who you are, or what you do, your work will make a significant difference.

We go the extra mile, every day, because we truly care. We work together as a team to achieve our life changing therapies. Our talented colleagues help to build other people’s futures, so can you. We empower each other to be our best.

We have access to like-minded scientists and engineers, working in the latest technologies.

Our community of experts create new life-saving cures. Shaping the business’ future through collaboration. Our people are on a continuous professional development journey aided by a thought-provoking environment. A place for experts to be stretched, and future experts to be nurtured. We inspire creativity and deliver great science, and so can you.

Our supportive culture invites talent, while creating future innovators.

We’ll give you a place where you can learn, grow and contribute to the future of cell and gene therapy. We create opportunities and invest in our people, promoting ongoing learning.  Our defined career pathways provide opportunities for everyone to achieve their career potential.  We make a difference, and so can you.

Company info
Website
Telephone
+44 (0) 1865 783 000
Location
Windrush Court
Transport Way
Oxford
OX4 6LT
United Kingdom

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