AstraZeneca

Scientist - Analytical Development, Biotherapeutics

Location
Cambridge, England, Cambridgeshire
Salary
Negotiable
Posted
18 Feb 2021
Closes
18 Mar 2021
Ref
R-100721
Contact
AstraZeneca
Discipline
R & D , Scientific
Hours
Full Time
Contract Type
Permanent
Experience Level
Experienced (non-manager)

Scientist - Analytical Development, Biotherapeutics

Cambridge

Salary & Benefits Competitive

At AstraZeneca, we win through science, it's at the heart of our every success. That science is only possible when we all work together! - we'll always make sure you're clear about how your role is connected to our wider mission to really show what science can do.

Job Description

At AstraZeneca, we make a difference every day by delivering life-changing medicines to millions of people worldwide. Our purpose is ambitious and so is our approach. Becoming a more agile and creative company means building an inspiring culture where we celebrate ambitious thinking. We are curious, creative, and open to new insights. Join us and become part of an extraordinary place to work!

This is an exciting opportunity to work within our Global Analytical Sciences Group based at the Granta Park, Cambridge facility. You will be joining the team involved in method development, in-process testing and technology transfer. With an exciting research pipeline, this is a great time to develop your career with AstraZeneca. As part of the team you will play a meaningful role in early drug development programmes by supporting the analytical characterisation of novel proteins (from peptides to antibodies).

Typical Accountabilities

  • To develop new analytical methods and perform routine analysis of development samples (process development, batch release and stability) using HPLC, UPLC, electrophoresis (CE-SDS, iCIEF), spectroscopy and compendial methods
  • Explore new technology for novel protein based products, as well as train and oversee junior members in this area
  • Work as a member of the team to ensure CMC goals and objectives are met
  • Accurately perform analytical testing according to established methods and SOP's
  • Selection and development of new techniques with the team to further develop in-house technology
  • Drafting appropriate reports and process documents
  • Attend and perform presentations at team meetings and co-ordination with other groups across the AstraZeneca
  • Ensures that work is performed in accordance with appropriate Safety, Health & Environment (SHE), quality and compliance standards, e.g. Good Laboratory Practice (GLP)

Education, Qualifications, Skills and Experience

Essential

  • Candidate must possess a minimum graduate equivalent qualification with prior proven experience
  • Proven track record of analytical method development and method qualification/validation gained within a similar environment
  • Extensive theoretical and hands on experience of analytical chromatography techniques: including HPLC, UPLC (reversed phase, size exclusion, IEX), capillary gel electrophoresis techniques (including SDS-PAGE, IEF) and other lot release and stability methodologies
  • Good written and oral communication skills
  • Ability to work in a team environment

Desirable

  • Experience of developing, qualifying and trouble-shooting chromatographic methods for monoclonal antibody and novel protein-based products
  • MSc

Open Date 18/02/2021

Close Date 18/03/2021

As part of the application process for some roles at AstraZeneca, candidates may be asked to complete a series of online games, created by pymetrics, to assess certain candidate qualities to help evaluate potential match for the position. If the pymetrics process applies to this role, you will receive an email invitation with additional information following application. Pymetrics will not be used solely in our decision-making process but will help us gather additional insight.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, colour, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.