Seuss Consulting

Senior Scientist USP Process Development

14 Feb 2021
16 Mar 2021
Full Time
Contract Type
Experience Level
Experienced (non-manager)
Senior Scientist USP Process Development

Our client is dedicated to bringing innovative therapies or unmet medical needs to patients. In doing so each function is directly or indirectly responsible for the lives of patients. This responsibility should be part of our day-to-day working life by (i) living up to high quality standards and (ii) by recognizing the sense of urgency in areas of high medical need.

Purpose of the role
The purpose of the role is to be a senior level contributor in upstream process (USP) development. The Senior Scientist would have her/his areas of specialization that are company-wide well recognized.

Place in the Organization
The Process Development (PD) department at Amsterdam, consists of several (senior) scientists and (senior) technicians lead by a principal scientist, is a part of Product Development. PD Amsterdam is responsible for development of innovative process technologies, process development for clinical and commercial manufacturing of AAV-based gene therapy products.

Key result areas (major duties, accountabilities, and responsibilities)
  • Performs development of innovative process technologies in the area of upstream processing or animal cell culture for manufacturing of AAV.
  • Designs / outlines (masterminds) experimental plan. Writes / reviews / approves plans, process descriptions and experimental protocols.
  • Line (people) manager for 0-3 (senior) technicians. Mentors and trains (senior) technicians and other Scientists.
  • Coordinates / supervises the experiments in the lab and when necessary performs experiments her / himself.
  • Analyzes / reviews experimental results / data, writes / reviews reports (g. experimental report, overall development report).
  • Acts as key consultant for higher management on scientific matters on her / his area of expertise. Proactively proposes new strategies and out-of-the-box approaches.
  • Continuously updates her / himself with state-of-the-art technologies in the field and strives for higher scientific excellence.
  • Presents results in conferences, writes journal articles and scientific content of patent applications.

Qualifications & Skills
  • Holds a PhD (in Bioprocess Engineering or Upstream Processing or Animal Cell culture or similar).
  • Possesses minimum 4 years of post-PhD work experience.
  • Possesses extensive hands-on experience on animal cell culture in different bioreactor systems at different scales for production of complex biologics, e.g. gene therapy, viral vaccines, or therapeutic proteins.
  • Highly skillful in theory and practical aspects of bioreactors, animal cell culture processes and virus production.
  • Experienced in multiple areas from the followings: Process development, manufacturing process design, design of experiments (DoE), scale up / down, technology transfer, adeno associated virus (AAV), GMP manufacturing, pharmaceutical quality management systems, common technical documents (CTD).
  • Outstanding scientific writing skill demonstrated by publications and reports.
  • Fluent in English.

Core competencies
  • Scientific excellence, the passion for state-of-the-art technologies
  • Proactive attitude to look beyond the assigned tasks
  • High level of ownership of the assigned programs
  • Leader / team player with an attitude to mentor others
  • Flexible to act in a highly dynamic and demanding environment

Please contact Ian Wood, Senior Recruitment Consultant, +31 (0)6 26 65 71 71

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