AstraZeneca

Scientist- Cell Line Development

4 days left

Location
England, Cambridgeshire, Cambridge
Salary
Negotiable
Posted
09 Feb 2021
Closes
02 Mar 2021
Ref
R-100085
Contact
AstraZeneca
Discipline
R & D , Scientific
Hours
Full Time
Contract Type
Permanent
Experience Level
Experienced (non-manager)

Scientist- Cell Line Development - 14 Month FTC

Cambridge

Salary & Benefits Competitive

At AstraZeneca, we turn ideas into life changing medicines! Working here means being entrepreneurial, thinking big and working together to make the impossible a reality!

Job Description

Fully proficient in research area. With the ability to work without supervision. Capability to mentor, train and develop less experienced scientists.

Typical Accountabilities

  • Applies knowledge and expertise to generate and characterize stable cell lines for clinical supply of recombinant proteins in a timely fashion and to agreed quality standards
  • Develops and maintains a level of knowledge and capability, perhaps extending to specialist expertise in cell line development
  • Represents cell line development on relevant project teams, ensuring the provision of appropriate and timely data to the team
  • Independently, designs and carries out cell line development and technology development experiments that require experienced knowledge, and develops and validates test methodology and specifications to achieve project aims
  • Independently, assesses and reports data with an understanding of its reliability, interprets findings and draws conclusions and recommendations so that their significance can be appreciated
  • Provides training /guidance to junior scientists on technical and functional processes
  • Helps to develop new and innovative techniques and methodologies and draws up relevant investigations
  • Liaises with colleagues from other subject areas with the purpose of discussing project-related matters, sharing experiences and reporting progress
  • Develops own level of scientific competence by keeping abreast of relevant scientific developments, by collaborating with peer scientists or through contacts with internal groups
  • Ensures that work is performed in accordance with Safety, Health & Environment (SHE), quality and compliance standards, e.g. Good Laboratory Practice (GLP)

Education, Qualifications, Skills and Experience

Essential

  • Minimum Bachelors degree or equivalent and proven experience within stable cell line development, distinct advantage would be a PhD
  • Experience in the biopharmaceutical industry
  • Understanding of current principles, concepts and practical skills in molecular biology including expression plasmid design and construction, mammalian cell culture and stable mammalian cell line development
  • Understanding of regulations and relevant compliance systems related to own area of work
  • General understanding of other functions within Biopharmaceutical Development
  • Good communication skills
  • Good team working skills

Desirable

  • Specialist knowledge in stable cell line development
  • Experience with cell line screening technologies such as micro-bioreactor systems and cell culture automation
  • Experience with CHO cell culture

Open Date 09/02/2021

Close Date 01/03/2021

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, colour, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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