Scientist In Vivo Pharmacology, Immuno Oncology 18 Mth FTC

England, Cambridgeshire
31 Jan 2021
27 Feb 2021
R & D , Scientific
Full Time
Contract Type
Experience Level
Experienced (non-manager)

Scientist In Vivo Pharmacology - Immuno Oncology 18 Month Fixed Term Contract

At AstraZeneca, we're not afraid to do things differently. We're resetting expectations of what a bio-pharmaceutical company can be. This means we're opening up new ways to work, Pioneering cutting edge methods and bringing global teams together!

We're passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring big new ideas to life.

Are you ready to work on one of the most exciting pipelines in the Oncology industry?

AstraZeneca's vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer, and to ultimately eliminate cancer as a cause of death. A broad pipeline of next-generation medicines is focused principally on four disease areas - breast, ovarian, lung and haematological cancers.

We are currently seeking to recruit a hands-on laboratory based in vivo biologist, to support immuno-oncology research and development activities within Oncology (Cambridge UK).

The successful candidate will be a highly motivated laboratory-based Scientist with significant knowledge and expertise within in vivo experimentation.

Assigned work items will primarily involve in vivo experimentation allied to specific projects, studies and workstreams; but may also include other pharmacology related activities to support the in vivo function.

These may include more generalised collaborative efforts required to deliver in vivo support across the project portfolio.

The successful candidate will be expected to present findings at internal meetings and prepare precise technical reports, protocols, quantitative analyses, and maintain appropriate documentation.

Education, Qualifications, Skills and Experience


  • BSc/MSc in a biological science
  • Home Office Licence (PIL Modules A, B, and C) or equivalent qualification for animal work and experience working under Home Office Regulations (as a Personal Licence Holder)
  • Experience of murine tumour models and allied experimentation.
  • Significant expertise and knowledge concerning in vivo experimentation allied to research, drug development or toxicology.
  • Utmost integrity and ethical standards associated with animal experimentation.
  • Willingness to undertake hands-on in vivo work in a predominantly laboratory-based role.
  • Ability to design and independently run and analyse in vivo experiments
  • Strong attention to detail, communication skills and record keeping. Ability to independently analyse data with appropriate statistical testing.
  • Detailed proficiency in the English language, both writing and speaking
  • There will be a requirement to work flexibly; including occasional weekends if necessary.


  • Ability to independently develop and design ex-vivo and / or in vitro experiments to understand the effect of drugs in complex model systems.
  • Expertise in techniques for the analysis of immune function and phenotype (e.g. flow cytometry, proliferation, cytokine/chemokine release [e.g. MSD, ELISA], chemotaxis, target cell killing assays).
  • Experience with in vivo imaging methods, working with radioisotopes or viral vectors.
  • Experience preparing written scientific reports (e.g. manuscripts) and oral presentations (e.g. slides, posters).

If this role describes you, don't hesitate in applying today!

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