Scientist in Dowstream Process for Viral Vector Development

Canton of Basel-Landschaft (CH)
25 Jan 2021
24 Feb 2021
R & D , Scientific
Full Time
Contract Type
Experience Level
Experienced (non-manager)

Our client is a leading global player in the Pharmaceutical industry with global headquarters in Basel, Switzerland. They are undergoing a transformation with respect to culture and outside perception. The organisation focusses on novel therapies in Oncology and Ophthalmology and is also currently developing a world-leading pipeline in Neuroscience and Dermatology with one of the strongest pipelines of Phase II/III studies in the world.



We are currently looking for a Downstream Process Scientist in Viral Vectors Development to be based in Basel for a 10 month contract position.

Main Responsibilities:

As an DSP Scientist , you will perform testing and other activities supporting the department.

  • Plan, perform and document scientific experiments to contribute to project related scientific/technical activities (e.g., interpret and report results, generate and evaluate data, draw relevant conclusions, write reports).
  • Utilize complex equipment (AKTA™ systems, Spectrum® KrosFlo® Research 2i TFF System...). Schedule maintenance and qualification of instruments.



  • Communicate and address issues. Provide input on deviations and unexpected results from experiments. Perform safety and literature searches.



  • Provide efficient and robust downstream processes for the manufacture of DS.



  • Generate scientific documents to hand over to internal and/or external partners (e.g., TechOps, authorities, external companies) and support generation of international registration documents under adequate guidance from more experienced team members.



  • Work according to appropriate standards as defined in Quality Manual, SOPs, ethical, health, safety, environment (HSE), and information security (ISEC) guidelines; lead initiatives to ensure proactive compliance and continuous improvement

Qualifications and Experience:

  • Relevant working/residency permit or Swiss/EU-Citizenship required;
  • Relevant Bachelor's / Master's degree in biochemistry, bioprocessing, bioengineering or equivalent
  • At least 2 years experience in downstream processing of Lentiviral Vectors and/or viruses in an industrial environment.



  • Advanced knowledge in purification principles (process characterization and scaling up) and technologies in the field of Cell and Gene Therapy and experience in Biosafety regulations, BL-1 and BL-2. 
  • GMP and GLP experience