Senior Scientist Upstream Process Development

Location
Maryland, USA, Gaithersburg
Salary
£88579.04 - £104982.57 per annum
Posted
06 Jan 2021
Closes
28 Jan 2021
Ref
BBBH15683
Contact
Hollie Carolan
Discipline
R & D
Hours
Full Time
Contract Type
Permanent
Experience Level
Senior Management

Hobson Prior are currently looking for a Senior Scientist Upstream Process Development to join a late-stage biotech organisation, specialising in improving health all over the world through discovering, developing and commercializing pioneering vaccines to prevent serious diseases. This is a permanent position, located in Gaithersburg Maryland.

Job Responsibilities:

  • Accountable to design experimental work independently or with minimal supervision.
  • You will design and execute process development studies to develop a thorough understanding of operating and performance parameters.
  • To perform hands on work in a cell culture lab, specifically cell culture expansion, vaccine production as well as process scale up and implementation into GMP clinical production suites.
  • Generate, manage, evaluate, and maintain critical data in a highly organized manner. Provide reports for assessment by senior management.
  • Ability to process complex data and communicate clearly and timely the implications of the results.
  • Perform and analyse Design of Experiment studies to develop or optimizing processes to ensure a phase-appropriate, consistent, high-yielding and scalable upstream process.
  • Assist in scale up and optimization of early stage processes, support critical operations as needed in our GMP manufacturing facility and deliver materials for pre-clinical and clinical studies.
  • Provide reagents and other supplies for various projects and departments.
  • Collaborate and coordinate with colleagues from Discovery, Process Development, Analytical Development, Manufacturing, and QA/QC teams.
  • To support process characterization studies and tech transfer process. As needed, support process validation, including validation protocol writing, execution and report writing.
  • This position is expected to be mainly hands on in the laboratory.

Key Skills:

  • Ability to think critically, demonstrate troubleshooting and problem-solving skills.
  • Strong interpersonal, verbal and written communication skills are essential.
  • Excellent record keeping abilities to adequately record, analyse and document data generated in support of regulatory requirements.
  • Self-motivated with a strong sense of ownership in areas of responsibility and willingness to accept temporary responsibilities outside of initial job description
  • Comfortable in a fast-paced environment and able to adjust workload based upon changing priorities.
  • Ability to work and collaborate in cross functional teams, research, development, manufacturing in a fast pace and dynamic team setting.
  • High energy level and a positive outlook coupled with the requisite "can do" attitude and a willingness to do what it takes to achieve personal and organizational goals and overcome obstacles.

Requirements:

  • Requires PhD in relevant field or a minimum of 10 years relevant experience with a Master's degree.
  • Previous experience with suspension cell culture systems, vaccine and/or viral vector production is desired.
  • Solid and hands-on upstream experience is required. Multi-year industrial purification experience with vaccines/biologics is preferred; direct experience with virus-derived recombinant products and/or viral particles is a plus.
  • A previous track record of culture process development experience such as cell passaging, formulation of media, aseptic technique processing, and managing reagents.
  • Practical demonstration of hands on process development including use of statistical design of experiments is required.
  • Experience with automation technologies is desired.

Apply now:

If you are interested in learning more or applying to this exciting opportunity then please click "Apply" and upload a copy of your CV. Alternatively, for further details or to talk directly to a life sciences recruitment specialist directly, please select "Contact me" at the top of this page.

Hobson Prior is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Hobson Prior is acting as an Employment Agency in relation to this vacancy.