Research Scientist (Molecular Cell Biologist) Oncology

2 days left

Essex, England
21 Dec 2020
18 Jan 2021
R & D , Biology
Full Time
Contract Type
Experience Level
Experienced (non-manager)

Research Scientist (Molecular Cell Biologist) in Oncology, Bioscience

Location: Cambridge, UK

At AstraZeneca, we work together across global boundaries to discover, develop, manufacture and market prescription medicines that make a positive impact on the lives of patients as well as their families and communities.

Our vision is redefining cancer, redefining our solutions to cancer and restoring patients' lives. Our mission is to make a meaningful difference to patient health through great medicines that bring benefit for patients and add value for society!

In addition to our passion for the discovery of innovative new medicines, we understand the importance of flexibility in our work-life environment, and we offer a wide variety of benefits, services and programs that provide our employees the resources they need to pursue not only their work goals but also their life goals.

We are dedicated to building strong research teams that embrace the diversity of talents of team members and allow the larger group to grow and learn together to accomplish our collective goal to improve human health!

We are seeking a highly motivated Research Scientist with a background and interest in molecular and cellular biology to join the DNA damage response (DDR) team within the Oncology Bioscience group in Cambridge, UK.

As a lab-based scientist you will be responsible for developing and running cell-based assays to explore drug mechanisms-of-action and understand target biology.

You will generate compelling pre-clinical experimental data to validate novel drug targets, investigate mechanisms of drug sensitivity or resistance and identify combination opportunities.

Your efforts will contribute to the discovery of new drug candidates and help progress projects through clinical development.

You will be expected to maintain cell lines in culture, develop and perform cell-based assays including, but not limited to, cell proliferation and survival, cell cycle analyses, immunofluorescence and western blotting.

This role will provide you with the opportunity to contribute to a wide variety of projects spanning the entire drug discovery pipeline and collaborate with scientists across multiple disciplines.

Major Responsibilities

  • Maintaining mammalian cell lines in tissue culture
  • Designing, performing and interpreting cell biology and mechanism-of-action studies such as growth inhibition and survival assays, western blotting, cell cycle and immunofluorescence
  • Developing, implementing, and troubleshooting cell-based assays
  • Organising and clearly presenting experimental results to project teams
  • Generating and maintaining clear experimental records

Essential Requirements

  • Bachelors or Master's degree in cell biology or equivalent, with hands-on lab experience e.g. industrial placement year
  • Strong technical and experimental ability
  • Positive and collaborative team player with willingness to improve and learn new skills
  • Passion for experimental work with a desire to pursue a career from the lab
  • Organised and able to work to tight timelines

Desirable requirements

  • Cancer cell biology experience
  • Lab-based drug discovery experience in academic or pharmaceutical company setting

Does this describe you? If so, don't hesitate in applying today.

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