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Scientist III, Analytical Development Group

Employer
Oxford BioMedica (UK) Limited
Location
Oxfordshire
Salary
Competitive
Start date
30 Nov 2020
Closing date
28 Dec 2020

View more

Discipline
R & D , Scientific
Hours
Full Time
Contract Type
Permanent
Experience Level
Experienced (non-manager)

Job Details

Our employees are able to develop their careers in exciting new medical technologies, and so can you.

We are currently recruiting for a Scientist III to join the Analytical Development Group.  The purpose of this role is assist in the development and implementation of new and existing analytical methods and techniques as required by the platform and their subsequent validation and qualification for application within a GMP environment.

Your responsibilities in this role would be:

  • Assist in the development and implementation of new and existing analytical methods and techniques as required by the platform.
  • Assist in investigative, pre-validation, validation and qualification projects for assays as part of the Analytical Development Group for GMP and to support GLP/GCP and research activities where necessary.
  • Design and conduct experiments /investigations in accordance with correct methodologies and procedures under the direction of the Principal or Senior Scientists.
  • Ensure a high standard of record keeping and documentation of experiments and investigations in order that information is clearly captured and disseminated and reported. Including the writing and reviewing of technical documents such as study documentation, validation plans, SOPs etc.
  • Analyse and interpret data and present/document the results at internal meetings and external venues such as conferences.
  • Assist in the robust technical transfer of methods cross-departmentally.
  • Share scientific knowledge through regular team/department meetings and presentations

To be successful in this role, you will have the following skills and experience:

  • BSc/MSc or PhD  in an associated subject
  • Essential Requirements:
  • Operating, developing, troubleshooting and validating of analytical methods.
  • Good knowledge/experience of analytical instrumentation and qualification procedures.
  • In-depth, hands-on expertise and up-to-date knowledge of bio-analytical methodologies.
  • Experience in qPCR, immunoassays (e.g. ELISA) and/or tissue culture essential.
  • Desirable Requirements:
  • Experience of molecular biology methodologies/techniques.
  • Experience in automation of analytical methods.
  • Experience in HPLC/HPLC-MS and/or ddPCR and/or flow cytometry.
  • Experience in analytical testing in support of viral vector production and T-cell therapies.
  • Experience of working to GMP.
  • Knowledge of Statistics (and/or DOE, QbD).
  • Knowledge of aggregation and/or sub-visible particle methods
  • Personal Attributes:
  • Credible and confident communicator (written & verbal) at all levels.
  • Ability to work accurately in a busy and demanding environment, adhering to deadlines/timescales
  • Self-motivated with the ability to work proactively using own initiative.
  • Committed to learning and development.
  • Attention to detail – Conscientious
  • Well organised and follows up on actions and strives for efficiencies
  • Do you want to feel inspired every day? We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment and team work, and so can you.

    Collaborate. Contribute. Change lives

    No agencies please

    Company

    Oxford Biomedica is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, Oxford Biomedica has more than 25 years of experience in viral vectors, the driving force behind the majority of gene therapies.  

    Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patient’s cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients’ cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).  

    Oxford Biomedica collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise. 

    Oxford Biomedica, a FTSE4Good constituent, is headquartered in Oxford, UK. It has locations across Oxfordshire, UK and near Boston, MA, US. Learn more at www.oxb.comwww.oxbsolutions.com, and follow us on LinkedInTwitter and YouTube

    Life at Oxford Biomedica

    We value everyone’s unique contribution, we appreciate everyone’s individuality, and every job matters.

    Your contributions are recognised and appreciated. Your work-life balance matters. We recognise, develop and use your strengths. It’s a place where you are valued as a whole person, as an individual and as part of a team.

    No matter who you are, or what you do, your work will make a significant difference.

    We go the extra mile, every day, because we truly care. We work together as a team to achieve our life changing therapies. Our talented colleagues help to build other people’s futures, so can you. We empower each other to be our best.

    We have access to like-minded scientists and engineers, working in the latest technologies.

    Our community of experts create new life-saving cures. Shaping the business’ future through collaboration. Our people are on a continuous professional development journey aided by a thought-provoking environment. A place for experts to be stretched, and future experts to be nurtured. We inspire creativity and deliver great science, and so can you.

    Our supportive culture invites talent, while creating future innovators.

    We’ll give you a place where you can learn, grow and contribute to the future of cell and gene therapy. We create opportunities and invest in our people, promoting ongoing learning.  Our defined career pathways provide opportunities for everyone to achieve their career potential.  We make a difference, and so can you.

    Company info
    Website
    Telephone
    +44 (0) 1865 783 000
    Location
    Windrush Court
    Transport Way
    Oxford
    OX4 6LT
    United Kingdom

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