Senior Scientist - NK Cells
- Employer
- Barrington James
- Location
- Ireland (IE)
- Salary
- Negotiable
- Start date
- 27 Nov 2020
- Closing date
- 4 Dec 2020
View more
- Discipline
- R & D , Scientific
- Hours
- Full Time
- Contract Type
- Permanent
- Experience Level
- Experienced (non-manager)
Job Details
Position Information:
I’m currently working with a fast growing, innovative cell therapy company that develop of best, in class, off the-shelf/alloheneic natural (NK) cell therapies. They are looking for an exceptional scientist to joing their expanding R&D team.
Key Responsibilites:
- Undertake R&D and development to meet company objectives
- Design and development of NK specific CAR constructs
- Design and testing of CAR-NKs using proprietary scFvs
- Optimization of gene editing using CRISPR/Cas9 in NK cells.
- Development of viral and non-viral gene modification approaches in NK cells using a variety of techniques, including AAV, transposases.
- Develop appropriate assays/pre-clinical models to assess activity of genetically modified NK cells
- Present progress Leadership team and at R&D group meetings
Essential Requirements:
- Ph.D. in Cell Biology, Molecular Biology, Immunology, Bioengineering or a related discipline
- 3+ years of experience of the field of cell therapy, NK biology or immunotherapy.
- Cell engineering experience preferred
Additional Requirements:
- A strong understanding of immunology and ideally experience in NK cell biology
- Expertise in T and NK cell-based assays (e.g. ELISA/ELISpot, FACS, cancer cell killing, multiplex cytokine assays etc.)
- Expertise in molecular biology; viral (including AAV) and non-viral transduction experience, cellular transfection, gene editing with CRISPR/Cas9, cell culture (primary, cell lines, spheroids) as well as prior in vivo work would be advantageous
- Excellent verbal and written communication skills
- Strong time-management and organizational skills coupled with a strong work ethic.
- A methodical approach to analyzing and processing data
- Good time management and organizational skills
- The ability to work independently
- Exercises judgment within broadly defined practices and policies in selecting methods, techniques and evaluation criteria for obtaining results.
- Collaborative team player who has the ability to think and act quickly; identify creative solutions to complex problems, communicate and act quickly to the benefit of the team and meeting objectives.
- Strong attention to detail with the ability to articulate quality related risks and potential impact.
- Proficient knowledge of MS Word, Excel, PowerPoint & Outlook
Company
We’re great at what we do. A collection of the worlds finest Life Science recruiters working for the worlds best Life Science consultancy.
Originally, a purely contingency and contract recruiter, focused in the UK, Barrington James is now a sophisticated, highly effective provider of human resources solutions up to full RPO, partnering the pharma, medical devices, and healthcare industries right across the globe.
- Website
- https://barringtonjames.com/
- Telephone
- 01293 776644
- Location
-
Victoria House
Consort Way
Horley
Surrey
RH6 7AF
GB
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