Skip to main content

This job has expired

Scientist IV, Computer-aided Biology

Employer
Oxford BioMedica (UK) Limited
Location
Oxfordshire
Salary
Competitive
Start date
24 Nov 2020
Closing date
22 Dec 2020

View more

Discipline
R & D , Scientific
Hours
Full Time
Contract Type
Permanent
Experience Level
Experienced (non-manager)

Job Details

Our employees are able to develop their careers in exciting new medical technologies, and so can you.

 

Oxford Biomedica’s Computer-aided Biology (CAB) Group is part of the Platform Research Department. CAB’s remit is to contribute to the research and development of new and existing assays to support the development of Oxford Biomedica’s pipeline. CAB evaluate and implement new technologies to improve the performance and efficiency of analytical work streams using cutting-edge advanced robotics. The group also assist in validation and qualification of assays and equipment for use in QC release testing.

Your responsibilities in this role would be:

  • To assist in the implementation of digitally enabled robotics targeting key bottle necks in analytical testing
  • To develop lab automation workflows
  • To liaise with analytical departments (GMP and Research) in order to facilitate the execution of high-throughput automated protocols
  • To assist with the execution of large batch experiments for Process Characterisation across different departments
  • To perform data analysis using complex Excel spreadsheets
  • To assist with the implementation of ELN for automated workflows
  • To write, revise SOPs and provide training
  • To develop new lentiviral vector transduction workflows on automated liquid handlers
  • To assist in the execution of complex Design of Experiments (DoE) protocols

To be successful in this role, you will have the following skills and experience:

  • Degree in Life Sciences/Science/Analytical Science with relevant experience in academia or industry
  • Experience with digitally enable robotics and automation
  • Good experience in sterile cell culture using mammalian cells
  • Extensive research and development background in protein and molecular biology techniques (nucleic acid extraction, quantitative real-time PCR, ELISA)
  • Knowledge of basic virology, lentiviral vectors and gene therapy
  • A strong background in assay development
  • Experience of automated data analysis and/or visualization software e.g. JMP
  • Desirable experience in flow cytometry
  • Desirable knowledge of different coding languages
  • Desirable experience in working in GMP-like environments

Your personal attributes will include:

  • Proven problem solving skills/diagnosing faults/resolving qualification issues
  • Exceptional written and verbal communication skills
  • Excellent interpersonal skills
  • Excellent planning and time management ability
  • Ability to undertake projects to agreed timelines and adapt to rapid changes in project priorities
  • Ability to train operators
  • Ability to work independently and autonomously to support validation projects and communicate progress and any issues via team meetings and project meetings

Do you want to feel inspired every day? We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment and team work, and so can you.

Collaborate. Contribute. Change lives

No agencies please

Company

Oxford Biomedica is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, Oxford Biomedica has more than 25 years of experience in viral vectors, the driving force behind the majority of gene therapies.  

Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patient’s cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients’ cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).  

Oxford Biomedica collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise. 

Oxford Biomedica, a FTSE4Good constituent, is headquartered in Oxford, UK. It has locations across Oxfordshire, UK and near Boston, MA, US. Learn more at www.oxb.comwww.oxbsolutions.com, and follow us on LinkedInTwitter and YouTube

Life at Oxford Biomedica

We value everyone’s unique contribution, we appreciate everyone’s individuality, and every job matters.

Your contributions are recognised and appreciated. Your work-life balance matters. We recognise, develop and use your strengths. It’s a place where you are valued as a whole person, as an individual and as part of a team.

No matter who you are, or what you do, your work will make a significant difference.

We go the extra mile, every day, because we truly care. We work together as a team to achieve our life changing therapies. Our talented colleagues help to build other people’s futures, so can you. We empower each other to be our best.

We have access to like-minded scientists and engineers, working in the latest technologies.

Our community of experts create new life-saving cures. Shaping the business’ future through collaboration. Our people are on a continuous professional development journey aided by a thought-provoking environment. A place for experts to be stretched, and future experts to be nurtured. We inspire creativity and deliver great science, and so can you.

Our supportive culture invites talent, while creating future innovators.

We’ll give you a place where you can learn, grow and contribute to the future of cell and gene therapy. We create opportunities and invest in our people, promoting ongoing learning.  Our defined career pathways provide opportunities for everyone to achieve their career potential.  We make a difference, and so can you.

Company info
Website
Telephone
+44 (0) 1865 783 000
Location
Windrush Court
Transport Way
Oxford
OX4 6LT
United Kingdom

Get job alerts

Create a job alert and receive personalised job recommendations straight to your inbox.

Create alert