Most drug discovery programs focus on just 2% of our DNA – those areas that have been proven to code for proteins.
That means there’s a huge amount of genomic “dark matter” which could hold the key to developing drugs that save lives and tackle some of the most challenging diseases we face.
As a molecular biologist with a strong understanding of bioinformatics, you could play a crucial role in unlocking the non-coding genome to advance human health.
We’re working with a company who have developed a unique approach to target finding on this new genomic frontier, combining machine learning, bioinformatics and novel molecular biology techniques to identify novel targets in lymphocytes that will form the basis of new treatments for autoimmune diseases. They are looking for a New Targets Lead to come and join their growing team in Oxford.
You’ll take the potential targets that their platform has identified and triage them into a portfolio of drug discovery programs, assessing druggability, effectiveness and impact as well as the competitive landscape to inform your choices.
You’ll act as the link between the company’s computational and platform technology scientists, validate novel targets with in vitro experiements and play a critical role in defining the scientific strategy of the organisation.
Ultimately, it will be your responsibility to find the signal in the noise in a truly novel and unexplored area of the human genome – the opportunity for scientific innovation is exceptional.
While doing this, you’ll also play a formative role in the building of a high-potential startup, so your career prospects will be significant and you’ll see substantial reward through share options.
We’re looking for a PhD-qualified drug discovery scientist with a strong track record of successful target identification and validation. You’ll have spent some of your career working in a Pharmaceutical or Biotech company and will demonstrate an excellent understanding (ideally backed up by practical experience) of bioinformatic approaches, as well as proven expertise in immunology.
If you have the background we’re looking for and the opportunity to mine untouched areas of the genome for novel targets sounds like the next step in your career, then apply online or get in touch on firstname.lastname@example.org.
We’re looking forward to hearing from you.