Process Development Lead *** rAAVs / Viral Vector NBEs

Employer
Advanced S&S (Medical / Clinical)
Location
Remote then Mainland Europe Post-Covid
Salary
On Application
Closing date
14 Oct 2020

View more

Discipline
Manufacturing, Engineering, Process, R & D , Biotechnology, Genetics and Genomics
Hours
Full Time
Contract Type
Permanent
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Upstream & Downstream Process Development Lead AAVs

Note: This role is located in Belgium. Post-Covid a full and generous relocation package is available. Until then home working is offered as standard!

Note: My client has committed to do Digital Hiring and Digital On-Boarding process in place to allow a smooth transition during the outbreak. During the next period, new hires will be allowed to work from home, until such a time occurs when normal working returns. At this point, if you are not residing in Belgium the role will require you to relocate to Brussels, which is fully paid for by my client, but until this time, this and many other roles are using remote working.

This role can be a Director or Associate Director Grade, dependent upon your experience and capabilities!

About the Client

The company that is offering this position is a biopharmaceutical company with global footprint and strong values and care about their employees:-

  • They have a rich history of marketed products during the last 10 years and they were one of the first to adopt the monoclonal Antibodies. The aim is now to expand the portfolio by including a new platform dedicated to AAV gene therapies.
  • The investment over the last years in VV has been gradual and one of the main focuses will be to move the R&D current pipeline they have to the clinical.
  • The company growing paces around 15-20% year-on-year, and they have investing in R&D by >21% of T/O over last 5 years for a number of therapies areas including rare diseases, and wider disease targets.
  • As part of the company strategy, they have pulled together a team specialized in licensing and alliances scouting to untapp future research collaborations.

 About the role:

We are looking for previous experience in process development / senior scientist with PhD or Masters (MEng, MBio) and 5-8 years of industrialization experience (could be less with Post Docs) in process development for biotechnology products, where 2-3 years out of them should be specifically on AAV / LV development, including process characterization, any direct Phase 2 scale-up for Viral Vector NBE’s would also be useful but not essential.

The candidate will be one of a handful experts internally responsible for different aspects of manufacturing and technical management, with this role focusing on the up- mid- and downstream development, so you will have designed the experiments in your current role, worked with analytical and the wet labs, to develop and shape successful VVs manufacturing. 

Good understanding of FDA and EMA requirements for CMC packages for ATMPs.

You will have multiple interactions with teams working in analytics, quality, project management, sterile packaging, clinical supply, and with external CDMOs MSAT teams.

This role is fundamental to develop the pipeline and execute process development programs to bring for clinical study rAAVs materials and support the regulatory fillings related to them. You will evaluate technology investments, to support multiple VV NBEs in the project pipeline.

Package & Benefits

This role is based in Brussels, Belgium and comes with full relocation, including disturbance allowances, temporary high-quality apartment, schooling if needed as well as a tax reduction package (for non-Belgium Nationals). The role comes with a car, bonus and stock plan, and there is ample opportunity to grow in this organization. During the Covid outbreak, you will work from home in your country of origin until travel restrictions are lifted!
 

To Apply!

To learn more and apply for this role, please send your CV with a covering note to cv@advtalent.com. You can also contact Javier Monfort or Matt Greig on +44 (0)207 801 3385 or +44 (0)207 801 3386 for an initial discussion about the role and other projects.

About Advanced Search & Our Network

Advanced Search, has a network of affiliated companies including ADV Regulatory, and ADV Talent Partners. Together, we are specialists in Regulatory Affairs and Life Sciences recruitment especially around mAbs and biologicals for roles in R&D and Commercialization and have been established and hiring in this area since 2005.

Our team know our subject matter areas and our mission is to help you grow your career each and every step of the way. We have helped many of today's leading companies develop strong regulatory sciences functions and are known for hiring complimentary teams that work well with each other, at owner-contributor, strategy leading and people management levels.

We provide a high level of service because we believe this matters.

Contact us today to see how we can help you, make that next career move on

+44 (0)20 7801 3380

All applications are kept in confidence and we invite applications from all members of the Academic, Research & Development based bio-/pharmaceutical community.

Advanced Regulatory is a new recruitment organisation. Our consultants are industry known and highly experienced in Regulatory Affairs recruitment. We have assembled a team with competencies in databased contingency recruitment, Search & Selection as well as Creative & Campaign management. Our specialism is Regulatory Affairs. We know that successful submissions are underpinned not by one but many people, all working in cohesion. Whether you require a new career position or a new recruit at junior, mid or senior level, we would like to assist you. Our remit is to provide Regulatory Affairs professionals at all levels to pharmaceutical, regulatory consulting, biopharmaceutical and clinical research organisations.

Contact Us
  • Suite 8, Penhurst House
  • 352-356 Battersea Park Road
  • SW11 3BY
  • GB
  • +44 (0)20 7801 3388
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