Scientist IV, Analytical Development Group (12 month maternity cover)

Oxford BioMedica (UK) Limited
Closing date
9 Oct 2020
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We drive credible science to realise incredible results, and so can you.

Oxford Biomedica’s Analytical Development Group provides first rate support for external partnerships and for the company’s portfolio of cell and gene therapies. Working closely with manufacturing, clinical and analytical services at all stages of development, this team is responsible for assay development and subsequent validation to support the GMP manufacturing process and early phase development.

We are currently recruiting for a Scientist IV to join the team for a 12 month maternity cover.  The purpose of this role is to assist in the development and implementation of new and existing analytical methods and techniques as required by the platform and their subsequent validation and qualification for application within a GMP environment.

Your responsibilities in this role would be:

  • Assist in the development and implementation of new and existing analytical methods and techniques as required by the platform.
  • Support innovation and development of new analytical assays as well as improvement and optimisation of current methods for Lentiviral Vector products characterisation.
  • Contribute to evaluation of new analytical methods and technologies.
  • Assist in investigative, pre-validation, validation and qualification projects for assays as part of the Analytical Development Group for GMP and to support GLP/GCP activities where necessary.
  • Design and conduct experiments /investigations in accordance with correct methodologies and procedures under the direction of the Principal or Senior Scientists.
  • Ensure a high standard of record keeping and documentation of experiments and investigations in order that information is clearly captured and disseminated and reported. Including the writing and reviewing of technical documents such as study documentation, validation plans, SOPs etc.
  • Analyse and interpret data and present/document the results at internal meetings, client meetings and external venues such as conferences.
  • Ensure robust technical transfers of method cross-departmentally.
  • Share scientific knowledge through regular team/department meetings and presentations

To be successful in this role, you will have the following skills and experience:

  • BSC/ PhD or extensive relevant experience  in an associated subject
  • Essential Requirements:
    • Operating, developing, troubleshooting and validating of analytical methods.
    • Good knowledge/experience of analytical instrumentation and qualification procedures.
    • In-depth, hands-on expertise and up-to-date knowledge of bio-analytical methodologies.
    • Experience in qPCR, immunoassays (e.g. ELISA) and/or tissue culture essential.
    • Knowledge of aggregation and/or sub-visible particle methods.
    • Biophysical and biochemical protein characterisation.
  • Bonus Requirements
    • Experience of molecular biology methodologies/techniques.
    • Experience in automation of analytical methods.
    • Experience in HPLC/HPLC-MS and/or ddPCR.
    • Experience in analytical testing in support of viral vector production and T-cell therapies.
    • Experience of working to GMP.
    • Knowledge of Statistics (and/or DOE, QbD).
  • Required Personal Attributes
    • Credible and confident communicator (written & verbal) at all levels.
    • Ability to work accurately in a busy and demanding environment, adhering to deadlines/timescales.
    • Self-motivated with the ability to work proactively using own initiative.
    • Committed to learning and development.
    • Attention to detail – Conscientious.
    • Well organised and follows up on actions and strives for efficiencies

Do you want to feel inspired every day? We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment and team work, and so can you.

Collaborate. Contribute. Change lives

No agencies please

About us

We are a pioneering gene therapy business, and our mission is delivering life-changing gene therapies to patients.  We work together, motivated to make a difference, and so can you.

We are pioneers; no one else does what we do

Gene therapy is the treatment of disease by the delivery of therapeutic DNA into a patient’s cells. It is transforming medicine as we know it; long term and potentially curative treatments for a wide range of diseases are now possible.

We are at the forefront of this exciting area. We have a strong reputation in gene therapy, with world-leading expertise in lentiviral vectors. We have a leading, integrated platform of exclusive technologies to design, develop and bioprocess unique gene-based medicines, both in-house and with partners.

We drive credible science to realise incredible results.

Whether you’re motivated by the discovery and development of product candidates within Research, or by cutting edge tools and technologies including AI and automation of our contract development and manufacturing organisation, we can offer you a career like no other. We are excited about our future. Join us and change lives.

Life at Oxford Biomedica

We value everyone’s unique contribution, we appreciate everyone’s individuality, and every job matters.

Your contributions are recognised and appreciated. Your work-life balance matters. We recognise, develop and use your strengths. It’s a place where you are valued as a whole person, as an individual and as part of a team.

No matter who you are, or what you do, your work will make a significant difference.

We go the extra mile, every day, because we truly care. We work together as a team to achieve our life changing therapies. Our talented colleagues help to build other people’s futures, so can you. We empower each other to be our best.

We have access to like-minded scientists and engineers, working in the latest technologies.

Our community of experts create new life-saving cures. Shaping the business’ future through collaboration. Our people are on a continuous professional development journey aided by a thought-provoking environment. A place for experts to be stretched, and future experts to be nurtured. We inspire creativity and deliver great science, and so can you.

Our supportive culture invites talent, while creating future innovators.

We’ll give you a place where you can learn, grow and contribute to the future of cell and gene therapy. We create opportunities and invest in our people, promoting ongoing learning.  Our defined career pathways provide opportunities for everyone to achieve their career potential.  We make a difference, and so can you.

Contact Us
  • Windrush Court
  • Transport Way
  • OX4 6LT
  • United Kingdom
  • +44 (0) 1865 783 000
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