Associate Scientist / Scientist - Late Stage Formulation
Salary & Benefits: Competitive
At AstraZeneca we win through science, it's at the heart of our every success. But science is only possible when we all work together - we'll always make sure you're clear about how your role is connected to our wider mission to really show what science can do!
Scientific position responsible for late-stage formulation development of biologic products.
Design and execute formulation risk assessments and characterization studies, and develop formulation control strategies for Drug Substance and Drug Product. Ensure robustness of intended commercial formulations, suitability for intended use of container closure/packaging systems, and in-use compatibility with clinical administration components.
Exercise technical discretion and scientific rigor in experimental protocol design, data analysis, and results interpretation. Author marketing applications and support regulatory responses to approval. Develop new strategies and approaches to advance late-stage formulation development and deliver scientific and operational objectives.
Knowledge of protein biochemistry and degradation mechanisms, biopharmaceutical manufacturing processes, combination drug products, and/or biophysical analytical methods is required. Hands-on experience with high-performance size exclusion chromatography (HPSEC), particle characterization and sizing (e.g. light obscuration), and aggregate characterization methods are strongly preferred. Experience with formulation and biopharmaceutical development, characterization, control strategy, quality risk management, and/or CMC regulatory guidance and filings is preferred. Skills leading, planning, and executing complex projects on tight timelines are important. High degree of self-motivation and drive for results are critical.
B.S. , M.S. or Ph.D in chemistry, biochemistry, pharmaceutical sciences, engineering, applied sciences, or related field.
Skills and Abilities:
Develops creative solutions to complex problems, but likewise proficient at anticipating and heading off potential issues. Demonstrates strong scientific thinking and project organizational skills to navigate projects forward. Effectively and efficiently explains and presents complex scientific concepts to diverse audiences. Displays ability to resolve conflicts through effective interpersonal communications and cross-functional collaborations. Excels at making good decisions, priority setting, and mentoring team members.
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, colour, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Open date: 10th September 2020
Closing date: 9th October 2020