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Technical Manager, MSAT

Employer
Oxford BioMedica (UK) Limited
Location
Oxford
Salary
Competitive
Start date
8 Sep 2020
Closing date
6 Oct 2020

View more

Discipline
R & D , Biotechnology
Hours
Full Time
Contract Type
Permanent
Experience Level
Management

Job Details

Do you want to develop your career in exciting new medical technologies? We deliver life-changing gene therapies to patients, and so can you.

Oxford Biomedica’s Manufacturing, Science and Technology Team is responsible for process and technology development activities from early concept through to product registration for market approval, to ensure that OXB’s new and existing manufacturing processes can deliver the productivity, performance, quality and cost benefits required in line with regulatory guidance.

We are currently recruiting for a Technical Manager to join the team.  One of the main purposes of this role is to provide technical input and oversight within the MSAT function to enable successful introduction of new product/technology to our Manufacturing Processes.

Your responsibilities in this role would be:

 Lead and manage team of MSAT Scientists / Process engineers focused on Vector Substance Manufacture

  • Accountable for delivery of multiple technical projects/tasks working directly with customers, OXB cross functional teams to ensure project time lines are met according to internal and/or customer needs
  • Proactively identifying and communicating risk and issues related to drive continuous improvement and increase process robustness
  • Driving the introduction of new technology / capability to expand OXB offering
  • Provide subject matter expertise (SME) within OXB on specific process units related to vector substance manufacture, suitability of raw materials for GMP use, on technology transfer approach
  • Support investigations related to clinical and commercial manufactures of vector substance
  • Ensures compliance with OXB’s Quality, Safety and Environmental systems and procedures
  • Maintains awareness of external technologies and patent landscape in order to ensure OXB remains at the forefront of the industry
  • Maintains awareness of regulatory guidance and their potential impact on OXB process
  • Develop and maintain relationships with key suppliers and technology providers

 To be successful in this role, you will have the following skills and experience:

  • Degree or equivalent experience in a relevant Science (e.g. Biological sciences, Biochemical Engineering, Biomedical Engineering) with substantial relevant experience in an industrial setting
  • Strong knowledge of bioprocessing
  • Practical experience in GMP manufacture
  • Significant experience of GMP manufacturing and knowledge of quality and regulatory requirements
  • Understands the health, safety and environmental aspects of the work carried out
  • Strong background in supporting regulatory submissions
  • Significant industrial experience in the scale up and industrialisation of GMP manufacturing bioprocesses, technical support & process trouble-shooting
  • Recognised SME in technical field of expertise covering areas such as technology transfer, optimisation and scale-up and GMP manufacturing operations

Do you want to feel inspired every day? We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment and team work, and so can you.

Collaborate. Contribute. Change lives

No agencies please.

Company

Oxford Biomedica is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, Oxford Biomedica has more than 25 years of experience in viral vectors, the driving force behind the majority of gene therapies.  

Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patient’s cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients’ cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).  

Oxford Biomedica collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise. 

Oxford Biomedica, a FTSE4Good constituent, is headquartered in Oxford, UK. It has locations across Oxfordshire, UK and near Boston, MA, US. Learn more at www.oxb.comwww.oxbsolutions.com, and follow us on LinkedInTwitter and YouTube

Life at Oxford Biomedica

We value everyone’s unique contribution, we appreciate everyone’s individuality, and every job matters.

Your contributions are recognised and appreciated. Your work-life balance matters. We recognise, develop and use your strengths. It’s a place where you are valued as a whole person, as an individual and as part of a team.

No matter who you are, or what you do, your work will make a significant difference.

We go the extra mile, every day, because we truly care. We work together as a team to achieve our life changing therapies. Our talented colleagues help to build other people’s futures, so can you. We empower each other to be our best.

We have access to like-minded scientists and engineers, working in the latest technologies.

Our community of experts create new life-saving cures. Shaping the business’ future through collaboration. Our people are on a continuous professional development journey aided by a thought-provoking environment. A place for experts to be stretched, and future experts to be nurtured. We inspire creativity and deliver great science, and so can you.

Our supportive culture invites talent, while creating future innovators.

We’ll give you a place where you can learn, grow and contribute to the future of cell and gene therapy. We create opportunities and invest in our people, promoting ongoing learning.  Our defined career pathways provide opportunities for everyone to achieve their career potential.  We make a difference, and so can you.

Company info
Website
Telephone
+44 (0) 1865 783 000
Location
Windrush Court
Transport Way
Oxford
OX4 6LT
United Kingdom

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