Senior Scientist, Analytical - Process R&D

Employer
Oxford BioMedica (UK) Limited
Location
Oxfordshire
Salary
Competitive
Closing date
29 Sep 2020

View more

Discipline
R & D , Scientific
Hours
Full Time
Contract Type
Permanent
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Our employees are able to develop their careers in exciting new medical technologies, and so can you.

Oxford Biomedica’s Process R&D team consists of experienced scientists and engineers that have extensive expertise in all aspects of upstream and downstream development.  PR&D take processes from the laboratory “bench” scale and apply process expertise and engineering fundamentals for delivery to Manufacturing.

We are currently recruiting for a Senior Scientist, Analytical to join the team.  The purpose of this role is to plan, execute and report relevant investigations and to support and supervise other members of the Group as needed to aid the Group Leader in meeting Group/Department objectives.

Your responsibilities in this role would be:

  • Perform analytical assays to support upstream and downstream process development activities, to inform process understanding and to deliver process characterisation activities.
  • Responsible for coordinating and executing the analytical support activities for all assigned process development projects.
  • Learn and implement laboratory techniques and demonstrate excellent levels of accuracy and quality when carrying out analytical analyses.
  • Carry out multiple laboratory-based assays each week and complete the data processing for these assays in a timely manner.
  • Perform, develop and optimise robust, efficient analytics for improving process monitoring and performance.
  • Support the implementation of new processes and analytical technologies by working with cross-functional departments to bring new analytical techniques in to PR&D.
  • Analyse and interpret data and present/document the results at internal team meetings and client meetings.
  • Generate reports and prepare scientific presentations as needed.
  • Write, revise, review and approve SOPs and technical reports.
  • Share scientific knowledge through regular team meetings and presentations.
  • Deputise for the Analytics Team Lead when required.

To be successful in this role, you will have the following skills and experience:

  • BSc, MSc or PhD (or equivalent) in a relevant Bioscience with an appropriate level of relevant experience.
  • Relevant laboratory experience in one or more of the following areas: Tissue Culture, qPCR, Molecular Biology or Protein Chemistry.
  • Knowledge of general cellular and molecular biology laboratory and analytical techniques
  • A sound understanding of viral vector analytical principles and processes
  • Practical experience in a range of bioprocess analytical techniques, such as but not limited to, cell-based assays, flow cytometry, nucleic acid extractions, qPCR, SDS PAGE, Western blot analysis, ELISA, and HPLC .
  • A sound understanding of basic biopharmaceutical process development activities .
  • Excellent aseptic technique.
  • In-depth knowledge of the regulatory requirements for analytical work (e.g. product specifications, stability testing guidelines etc.) is required
  • Capable of following company standard operating procedures and requirements.
  • Understanding of laboratory health and safety requirements and ensuring reports and junior staff adhere to these.
  • Competency in data capture reporting and management systems.
  • High level of familiarity with Microsoft Office.
  • High level of familiarity with the current literature relating to research projects.
  • Biotechnology industry experience in analytics, biological research and development or equivalent experience 
  • Experience with cell culture and downstream processing techniques.

Do you want to feel inspired every day? We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment and team work, and so can you.

Collaborate. Contribute. Change lives.

No agencies please

About us

We are a pioneering gene therapy business, and our mission is delivering life-changing gene therapies to patients.  We work together, motivated to make a difference, and so can you.

We are pioneers; no one else does what we do

Gene therapy is the treatment of disease by the delivery of therapeutic DNA into a patient’s cells. It is transforming medicine as we know it; long term and potentially curative treatments for a wide range of diseases are now possible.

We are at the forefront of this exciting area. We have a strong reputation in gene therapy, with world-leading expertise in lentiviral vectors. We have a leading, integrated platform of exclusive technologies to design, develop and bioprocess unique gene-based medicines, both in-house and with partners.

We drive credible science to realise incredible results.

Whether you’re motivated by the discovery and development of product candidates within Research, or by cutting edge tools and technologies including AI and automation of our contract development and manufacturing organisation, we can offer you a career like no other. We are excited about our future. Join us and change lives.

Life at Oxford Biomedica

We value everyone’s unique contribution, we appreciate everyone’s individuality, and every job matters.

Your contributions are recognised and appreciated. Your work-life balance matters. We recognise, develop and use your strengths. It’s a place where you are valued as a whole person, as an individual and as part of a team.

No matter who you are, or what you do, your work will make a significant difference.

We go the extra mile, every day, because we truly care. We work together as a team to achieve our life changing therapies. Our talented colleagues help to build other people’s futures, so can you. We empower each other to be our best.

We have access to like-minded scientists and engineers, working in the latest technologies.

Our community of experts create new life-saving cures. Shaping the business’ future through collaboration. Our people are on a continuous professional development journey aided by a thought-provoking environment. A place for experts to be stretched, and future experts to be nurtured. We inspire creativity and deliver great science, and so can you.

Our supportive culture invites talent, while creating future innovators.

We’ll give you a place where you can learn, grow and contribute to the future of cell and gene therapy. We create opportunities and invest in our people, promoting ongoing learning.  Our defined career pathways provide opportunities for everyone to achieve their career potential.  We make a difference, and so can you.

Contact Us
  • Windrush Court
  • Transport Way
  • OX4 6LT
  • United Kingdom
  • +44 (0) 1865 783 000
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