(Associate/ Senior) Medical Director (Clinical Director) Oncology

Closing date
30 Sep 2020

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Clinical Research, Clinical Development
Full Time
Contract Type
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Who We Are

At Roche, we are passionate about transforming patients' lives. We are committed to scientific and ethical rigor and to enabling access to medical innovations for all. 


Collaborative innovation is at the very heart of the organisation and we invest more than most other companies in R&D to drive this. We are proud of our history bringing patients first-in-class and best-in-class products. Roche has pioneered a number of novel treatments that have changed treatment paradigms of a number of diseases, including lung cancer. We have a truly differentiated portfolio across oncology, inflammation, immunology, infectious diseases, ophthalmology and neurology, which cover a uniquely broad spectrum of innovative solutions for healthcare needs of the future. Projects address all stages of prevention, diagnosis and treatment of disease as well as enhancing quality of life.  

(Associate / Senior) Medical Director - Roche - Oncology

We are looking for two motivated medical oncologists with clinical and drug development experience in the lung cancer therapeutic area.  

The first successful candidate would join the Alecensa Global Development Team. Alecensa is a highly selective, CNS active, oral ALK inhibitor that is currently approved for the treatment of patients with advanced NSCLC and has changed treatment outcomes for this group of patients. This position would offer opportunities for personal and professional development, as we look to build upon the foundations of the lung cancer data. 

The second successful candidate would join the Pralsetinib Development Team. Pralsetinib is a targeted RET tyrosine kinase inhibitor. RET-activating fusions and mutations are key disease drivers in many cancer types, including  lung cancer and treatment options that selectively target these genetic alterations are limited. Pralsetinib will be co-developed by Roche and Blueprint Medicines Corporation under the auspices of a licensing and collaboration agreement. This molecule is at an earlier stage of development than Alecensa and also offers many opportunites for both personal and professional development.  

With the ongoing need for more targeted therapies that may offer clinical benefit to patients, both positions reflect Roche's strategy of providing treatments tailored specifically to a patient's individual tumour profile and delivering truly personalised healthcare.

As the (Associate / Senior) Medical Director, you will have the opportunity to take on direct responsibility for the medical monitoring of studies as well as being the clinical science lead for subsequent data analysis and regulatory filings. The successful candidate will help to integrate findings and strategies across global drug development programs in the organization and more broadly in the field, leveraging up-to-date scientific knowledge towards executing innovative, effective clinical development plans.

The (Associate / Senior) Medical Director will be responsible for the design, implementation, monitoring, analysis, and reporting of global clinical studies and act as a clinical representative and content expert to a variety of functions (clinical operations, biostatistics, biomarker, regulatory affairs) within the organization. Both positions are global clinical research positions and provide the opportunity to redefine lung cancer treatment based on biomarker selection Because of the depth of expertise that resides within the organisation, both positions offer opportunities to work within a global, multi-site team and to build professional relationships across areas such as early stage, biomarker and diagnostic development. Other responsibilities may include building long-range strategic plans, establishing productive collaborations with research scientists and other internal and external experts, and assessment of in-licensing business development opportunities.

The successful candidate will be medically qualified. You will also have experience of treating lung cancer and a good knowledge of the lung cancer drug development landscape You will have a keen interest and understanding of drug development.

Skills & Experience:
  • Fluent in verbal and written English
  • Medically qualified with board certification/specialist status in medical oncology 
  • PhD qualified with experience in basic research and a track record of publication in leading scientific journals would be a plus, but not essential
  • Experience in the treatment of solid tumors, particularly lung cancer is favourable
  • Pharmaceutical or biotech industry drug development experience 
  • Experience of planning clinical trials and the attendant aspects such as study design, operational plans, regulatory considerations
  • Experience of working in a cross functional team 
  • Desire and ability to interact internal and external experts, clinical investigators and corporate partners
  • Working understanding of  the business dimensions of pharmaceutical drug development
  • Demonstration of the ability to evaluate, interpret and present complex scientific and clinical data
  • Excellent leadership, presentation and communication skills
  • Being able to participate in strategy discussions and provide expert opinion regarding current or future clinical development


Good luck with your application.


Roche is an equal opportunity employer.
Research & Development, Research & Development > Clinical Development

At Roche we believe life is incredibly precious and everyday we strive to solve some of the greatest and most complex health challenges facing humanity.  We help millions of people all over the world live longer and better lives every hour of every day and we’ve been writing scientific history for over 120 years. If you really know yourself and want to be part of our international family, dedicated to making a real impact on the world around us, the next step is yours.

Please visit our Careers Hub on PharmiWeb.Jobs:www.pharmiweb.jobs/minisites/roche-careers-hub/

Contact Us
  • P.O. Box 8
  • Welwyn Garden City
  • AL7 3AY
  • GB
  • +44 1707 36 6000
  • Mini-site: Roche
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