Most drug discovery programs focus on just 2% of our DNA – those areas that have been proven to code for proteins.
That means there’s a huge amount of genomic “dark matter” which could hold the key to developing drugs that save lives and tackle some of the most challenging diseases we face.
As a molecular biologist with fundamental expertise in immunology and the use of primary cells in research, you could play a crucial role in unlocking the non-coding genome to advance human health.
We’re working with a company who have developed a unique approach to target finding on this new genomic frontier, combining machine learning, bioinformatics and novel molecular biology techniques to identify lymphocytes that will form the basis of new drug targets for autoimmune diseases. They are looking for a Senior Scientist, Immunology to come and join their growing team in Oxford.
You’ll investigate the regulation of the non-coding genome in lymphocyte subsets using state of the art genomics approaches, and entirely novel ones of your own development.
You’ll work very closely with other laboratory and computational scientists to find new drug targets in this largely unexplored area of human genetics.
Ultimately, it will be your responsibility to conduct the experiments that lead to drug discovery programs in areas of serious unmet medical need.
While doing this, you’ll also play a formative role in the building of a high-potential startup, so your career prospects will be significant and you’ll see substantial reward through share options.
We’re looking for a PhD-qualified drug discovery scientist with expertise in cellular and molecular biology, or someone with an MSc and proven experience. You’ll have strong technical expertise with primary cell cultures and the development of primary assays, an excellent practical understanding of immunology and experience in Next Generation Sequencing. Time spent working in a Pharmaceutical or Biotech company would be strongly preferred.
If you have the background we’re looking for and the opportunity to mine untouched areas of the genome for novel targets sounds like the next step in your career, then apply online or get in touch on firstname.lastname@example.org.
We’re looking forward to hearing from you.