RESEARCH OFFICERS - CELLULAR IMMUNOLOGY & ASSAY DEVELOPMENT

ROLE OVERVIEW

The Research Officer will be responsible of designing, performing and analyzing experiments to support the validation of novel biologic targets in immuno-oncology and autoimmune diseases. We invite an interactive and creative individual who possesses sufficient scientific knowledge as well as some strong hands-on experience in the field to deliver the next wave of novel therapeutics to the patients.

SPECIFIC RESPONSIBILITIES:

 Design, optimize and validate functional immuno-oncology assays including but not limited to immunological multi-color cell surface and intracellular flow cytometric profiling, multiplex cytokine profiling, gene expression profiling, binding assays, primary human cell-based assays for the characterization of novel biological candidates.

 Perform cell culture, including primary human cultures, development and maintenance of cell lines.

 Write detailed protocols in English.

 Participate in day-to-day laboratory management.

 Perform data analysis on a regular basis and clearly communicate results in English.

 Maintain experimental records in electronic lab notebook format.

 Collaborate across functions to validate novel targets

 Assist with general laboratory duties including lab equipment maintenance, ordering and receiving of lab supplies.

 Comply with all safety guidelines

 Perform other relevant responsibilities as required.

REQUIREMENTS:

 Minimum of technical degree or equivalent in immunology, cellular biology or related life sciences

 3+ years of laboratory experience (industry experience preferred)

 Solid and demonstrable bench level experience in the development, validation and implementation of immunological assays

 Hands-on expertise in methodologies, reagents and instruments used for primary cell cultures, flow cytometry (mandatory), ELISA and cytokine analyses

 Experience with handling primary cells in BSL-2 level facilities, isolation of immune cells from human biological samples (PBMC) is mandatory

 Practical knowledge in data analysis using standard software (e.g. Excel, GraphPad, JMP, Flow cytometry dedicated software)

 Experience in antibody discovery and pharmaceutical industry is a plus

 Fluent English both written and verbal; proficiency in French is a plus

 Strong organizational skills with the capacity to handle multiple tasks simultaneously

 Ability to work independently as well as part of a cross-functional team

 Strong interpersonal communication skills