Invizius is developing second generation complement therapies to treat inflammatory, fibrotic and autoimmune disorders. Invizius’ proprietary approach was born out of over ten years of research by Dr Andy Herbert into how pathogenic microbes evade the human complement system. The novel mechanism of action enhances the activity of the body’s own complement regulators to effectively downregulate immune responses while maintaining antimicrobial protection. The lead product, H-Guard, addresses serious complement-driven complications of dialysis, and enables additional indications in other extra-corporeal treatments (ECMO, cardiopulmonary bypass). A second product is being developed to extend the period that patients can sustain home-based, peritoneal dialysis.
The company is working with Key Opinion Leaders from Manchester University NHS Foundation Trust, Karolinska Institutet, University of Heidelberg, University Medical Centre Groeningen, and University of Strathclyde. It is backed by Mercia, Downing, Calculus, and Syensqo, a corporate VC. Other investors include University of Edinburgh’s Old College Capital fund, Scottish Enterprise, and well-known life science investor, Dr Jonathan Milner.
For more information on Invizius, please visit: www.invizius.com
